Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Combination of antigens from multiple viral species
Patent
1988-12-14
1994-12-20
Wityshyn, Michael G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Combination of antigens from multiple viral species
4352351, 435236, 435238, 4352401, 4242071, 424819, A61K 3912, C12N 700
Patent
active
053744241
ABSTRACT:
A multivalent FeLV-infected feline vaccine composed of (1) a small but immunologically effective amount of inactivated feline leukemia virus; (2) a small but effective amount of an inactivated virus selected from the group consisting of Feline Rhinotracheitis Virus, Feline Calici Virus and Feline Panleukopenia Virus; and (3) a pharmaceutically acceptable immunologica adjuvant. Components (1) and (2) may be inactivated by any of the known techniques. The inactivated feline leukemia virus must be from subgroup A and is the Rickard isolate of the virus designated FeLV-A.sub.R1. This combination vaccine is effective in preventing Viremia, leukemia-associated syndromes, and deaths in cats caused by Feline Leukemia Virus, Feline Rhinotracheitis Virus, Feline Calici Virus and Feline Panleukemia Virus infections.
REFERENCES:
patent: 3944469 (1976-03-01), Bittle et al.
patent: 3966907 (1976-06-01), Jarrett et al.
patent: 4034081 (1977-07-01), Jarrett et al.
patent: 4086134 (1978-04-01), Jarrett et al.
patent: 4117112 (1978-09-01), Jarrett et al.
patent: 4264587 (1981-04-01), Pedersen et al.
patent: 4303644 (1981-12-01), Davis
patent: 4332793 (1982-06-01), Olson
patent: 4699785 (1987-10-01), Pedersen
patent: 4713325 (1987-12-01), Lutz
patent: 4772466 (1988-09-01), Allison et al.
Sarma et al, Virology, vol. 51, pp. 160-169, 1973.
Charreyre and Pedersen, "Evaluation of Humoral Immunity Test in FeLV Infected Cats" (pp. 197-200 and Enclosure A).
Veterinary Services Memorandum No. 800.50.
Possible Immunoenhancement of Persistent Viremia By Feline Leukemia Virus Envelope Glycoprotein Vaccines in Challenge-Exposure Situations Where Whole Inactivated Virus Vaccines Were Protective-N. C. Pedersen et al (pp. 123-148), Veterinary Immunology and Immunopathology (1986).
Crandell et al., "Development, Characterization, and Viral Susceptibility of a Feline (Felis Catus) Renal Cell Line (CRFK)", In Vitro, vol. 9, No. 3, 1973 pp. 176-185.
Sarma et al, "Subgroup Classification of Feline Leukemia and Sarcoma Viruses by Viral Interference and Neutralization Tests," Virology, (1973) 54:160-169.
Russell, et al., "The Specificity of Neutralizing Antibodies to Feline Leukaemia Viruses," Int'l J. Cancer (1978) 21:768-778.
Jarrett, "Feline Leukaemia Virus Subgroups," Feline Leukemia Virus-Developments in Cancer Research vol. 4, (1980) Hardy et al. Editors, Elsevier North Holland, Inc. pp. 473-479.
Jarrett & Russell, "Differential Growth and Transmission in Cats of Feline Leukaemia Viruses of Subgroups A and B," Int'l J. Cancern (1978) 60:871-874.
Chem. Abs. 99(17), B6704j.
Sarma et al., "Experimental Horizontal Transmission of Feline Leukemia Viruses of Subgroups A, B and C," J. Nat'l Cancer Inst., (1978) 60:871-874.
Bass Edmund P.
Kelsey William H.
Akorli Godfried R.
Gil Joseph C.
Miles Inc.
Mohamed Abdel A.
Wityshyn Michael G.
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