Multivalent avian influenza vaccines

Details Multivalent avian influenza vaccines Multivalent avian influenza vaccines

2005-10-06

2011-11-29

Mosher, Mary E (Department: 1648)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

C424S204100, C424S210100

Reexamination Certificate

active

08067013

ABSTRACT:
A vaccine composition and method which is effective in preventing or ameliorating Avian Influenza Virus infection is set forth herein. The vaccine contains at least two inactivated strains of avian influenza virus, wherein the combined haemoagglutinin (HA) total is at least about 200 HA/dose of the vaccine composition, and wherein each of the strains presents at least about 128 HA/dose, and further wherein one of the strains has the same HA subtype as that of a challenge virus, and wherein at least one of the strains has a different NA subtype than the challenge virus.

REFERENCES:
patent: 0399843 (1990-11-01), None
patent: WO 03/086453 (2003-10-01), None
Donatelli, et al., 2001 J Gen Virol 2001 vol. 82, pp. 623-630.
Fatunmbe et al. Avian pathology 1992 vol. 21 pp. 225-237.
Capua et al. Avian pathology 2002 vol. 32 pp. 47-55.
Avian Pathology, vol. 33(4), pp. 393-404, Aug. 2004, Avian Influenza: Recent Developments, Ilaria Capua, et al.
Journal Of Virology, vol. 73(7), pp. 5903-5911, Jul. 1999, A Mouse Model For The Evaluation Of Pathogenesis And Immunity To Influenza A (H5N1) Viruses Isolated From Humans, Xiuhua Lu, et al.
Avian Diseases, vol. 42(2), pp. 248-256, Apr. 1998, Efficacy Of Inactivated H5N2 Influenza Vaccines Against Lethal A/Chicken/Queretaro/19/95 Infection, Alejandro Garcia, et al.
Avian Pathology, vol. 21(2), pp. 225-237, 1992, Efficacy Of Avridine And Liposomes As Adjuvants For Avian Influenza Virus Antigens In Turkeys, O. O. Fatunmbi, et al.
Avian Pathology, vol. 28(3), pp. 245-255, Jun. 1999, Influence Of Virus Strain And Antigen Mass On Efficacy Of H5 Avian Influenza Inactivated Vaccines, Huntingdon, Cambs, GB, D. E. Swayne, et al.
André, F.E., “Development of Combined Vaccines: Manufacturers' Viewpoint,” Biologicals 22:317-321 (1994).
Capua et al., “Developments of a DIVA (Differentiating Infected from Vaccinated Animals) Strategy Using a Vaccine Containing a Herterologous Neuraminidase for the Control of Avian Influenza;” Avian Pathology 32, 47-55 (2002).
Cattoli, et al. “Comparison of three rapid detection systems for type A influenza virus on tracheal swabs of experimentally and naturally infected birds,” Avian Pathology, 33(4), pp. 432-437. (2004).
Clemens, J., et al., “Interactions between PRP-T Vaccine againstHemophilus influenzaeType b and Conventional Infant Vaccines Lessons for Future Studies of Simultaneous Immunization and Combined Vaccines,” In: Combined Vaccines and Simultaneous Administration. Current Issues and Perspectives (Eds. Williams, J.C., et al.) The New York Academy of Sciences, New York, pp. 255-266 (1995).
Ellis, et al., “Vaccination of Chickens Against H5N1 Avian Influenza in the Face of an Outbreak Interrupts Virus Transmission,” Avian Pathology 55(4), pp. 405-412 (Aug. 2004).
Goldenthal, K, L., et al., “Overview—Combination Vaccines and Simultaneous Administration. Past, Present, and Future,” In: Combined Vaccines and Simultaneous Administration, Current Issues and Perspectives (Eds. Williams, J.C., et al.) The New York Academy of Sciences, New York, pp. 1 XI-XV (1995).
Hadler, S.C., “Cost benefit of combining antigens,” Biologicals 22:415-418 (1994).
Insel, R.A., “Potential Alterations in Immunogenicity by Combining or Simultaneously Administering Vaccine Component,” In: Combined Vaccines and Simultaneous Administration. Current Issues and Perspectives (Eds. Williams. J.C., et al.) The New York Academy of Sciences, New York, pp. 35-47 (1995)).

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