Multiscanning confocal microscopy

Details Multiscanning confocal microscopy Multiscanning confocal microscopy

1993-12-15

1996-07-02

Nguyen, Thong Q.

Optical: systems and elements

Compound lens system

Microscope

359368, 359383, 359391, G02B 2126, G02B 2100

Patent

active

055328741

ABSTRACT:
A confocal microscope system has a turntable with object locations for mounting multiple samples to be examined in a ring. The turntable is rotated about an axis concentric with the ring. At least one confocal microscope optical system is mounted with components movable axially and radially relative to the ring so that an object region may be scanned through samples mounted in the object locations, each microscope system including a point image detector providing a signal output, and a demultiplexer for receiving the signal output and isolating signal segments associated with different sample locations, and a multiple channel signal processor processes the signals associated with different locations, and a control unit moves axially movable components of each optical system firstly to establish focus reference data for each object and then to control the focus of the microscope responsive to the focus reference data as it scans successive object locations.

REFERENCES:
patent: 5029996 (1991-07-01), Carter
patent: 5103338 (1992-04-01), Crowley et al.
patent: 5132526 (1992-07-01), Iwasaki
patent: 5212580 (1993-05-01), Coad et al.

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