Multiply-tritiated steroidal-20,17-spirolactones and their use a

Details Multiply-tritiated steroidal-20,17-spirolactones and their use a Multiply-tritiated steroidal-20,17-spirolactones and their use a

1985-04-12

1990-02-27

Maples, John S.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

540 13, 540 41, 514175, A61K 4902, A61K 3158

Patent

active

049044621

ABSTRACT:
Novel, multiple-tritiated steroid-20,17-spirolactones of general Formula I ##STR1## wherein --A--B-- is --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH-- or ##STR2## and --C--D-- is ##STR3## R is hydrogen or tritium and n is 0 or 1,
are usable as tracer materials for the detection of mineralocorticoid receptors.

REFERENCES:
patent: 3855208 (1974-12-01), Rutner et al.
patent: 3966714 (1976-06-01), Philippson
patent: 4450107 (1984-05-01), Nickisch et al.
patent: 4559331 (1985-12-01), Nickisch et al.

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