Multiplexed electronically programmable multimode ionization det

Details Multiplexed electronically programmable multimode ionization det Multiplexed electronically programmable multimode ionization det

1988-05-19

1989-11-07

Howell, Janice A.

Radiant energy

Invisible radiant energy responsive electric signalling

Including a radiant energy responsive gas discharge device

250382, G01N 2770

Patent

active

048794724

ABSTRACT:
Method and apparatus for detecting and differentiating organic compounds based on their electron affinity. An electron capture detector cell (ECD) is operated in a plurality of multiplexed electroncially programmable operating modes to alter the detector response during a single sampling cycle to acquire multiple simultaneous chromatograms corresponding to each of the different operating modes. The cell is held at a constant subatmospheric pressure while the electron collection bias voltage applied to the cell is modulated electronically to allow acquisition of multiple chromatograms for a single sample elution from a chromatograph representing three distinctly different response modes. A system is provided which automatically controls the programmed application of bias pulses at different intervals and/or amplitudes to switch the detector from an ionization mode to the electron capture mode and various degrees therebetween to provide an improved means of tuning an ECD for multimode detection and improved specificity.

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