Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Biological or biochemical
Reexamination Certificate
2011-04-26
2011-04-26
Smith, Carolyn L. (Department: 1631)
Data processing: measuring, calibrating, or testing
Measurement system in a specific environment
Biological or biochemical
C435S007100, C436S501000, C436S507000, C436S546000, C705S032000, C705S077000
Reexamination Certificate
active
07933721
ABSTRACT:
Clinical samples can be analyzed using microparticles to determine the serodiagnosis of a viral infection from two candidate viral infections of the same viral group. Serodiagnosis can be determined via a pooled population of subsets of microparticles, with the particles in the pooled population having a bound viral group-reactive antibody and the particles in each subset having at least one characteristic classification parameter that distinguishes between subsets. Viral antigens of antibodies of interest in the same viral-class as the viral group-reactive antibody can be bound to the viral group-reactive antibody on the microparticles, and subsequently exposed to a clinical sample. Binding and labeling can be used. Automated analysis of data from multiplexed flow analysis can determine the presence or absence of antibodies of interest in the sample, thereby diagnosing for two candidate viral infections in a single assay.
REFERENCES:
patent: 5981180 (1999-11-01), Chandler et al.
patent: 6046807 (2000-04-01), Chandler
patent: 6139800 (2000-10-01), Chandler
patent: 6268222 (2001-07-01), Chandler et al.
patent: 6366354 (2002-04-01), Chandler
patent: 6449562 (2002-09-01), Chandler et al.
patent: 6514295 (2003-02-01), Chandler et al.
patent: 6524793 (2003-02-01), Chandler et al.
patent: 6592822 (2003-07-01), Chandler
patent: 6599331 (2003-07-01), Chandler et al.
patent: 6632526 (2003-10-01), Chandler
patent: 6649414 (2003-11-01), Chandler et al.
patent: 6696304 (2004-02-01), Davies
patent: 6773812 (2004-08-01), Chandler et al.
patent: 2002/0115062 (2002-08-01), Fletcher et al.
patent: 2002/0172937 (2002-11-01), Dave et al.
patent: 2003/0219803 (2003-11-01), Jayasena et al.
patent: 2003/0232397 (2003-12-01), Brown et al.
patent: 2004/0009506 (2004-01-01), Stephan et al.
patent: 2004/0197769 (2004-10-01), Wong et al.
patent: 2004/0208350 (2004-10-01), Rea et al.
patent: 2004/0219517 (2004-11-01), Ecker et al.
Blitvich et al., “Epitope-Blocking Enzyme-Linked Immunosorbent Assays for the Detection of Serum Antibodies to West Nile Virus in Multiple Avian Species”, 2003, Journal of Clinical Microbiology, pp. 1041-1047.
“Antibody,” Wikipedia, http://en.wikipedia.org/wki/Antibody, 5 pages, webpage visited on Jan. 11, 2006.
Clarke et al., “Techniques for Hemagglutination and Hemagglutination-Inhibition with Arthropod-Borne Viruses,”American Journal of Tropical Medicine and Hygiene, vol. 7, No. 5, pp. 561-573, Sep. 1958.
Davis et al., “West Nile Virus Recombinant DNA Vaccine Protects Mouse and Horse from Virus Challenge and Expresses in Vitro a Noninfectious Recombinant Antigen That Can Be Used in Enzyme-Linked Immunosorbent Assays,”Journal of Virology, vol. 75, No. 9, pp. 4040-4047, May 2001.
Dreiseitl et al., “Comparing Three-class Diagnostic Tests by Three-way ROC Analysis,”Medical Decision Making, vol. 20, No. 3, pp. 323-331, Jul.-Sep. 2000.
Earley et al., “Report From a Workshop on Multianalyte Microsphere Assays,”Cytometry(Clinical Cytometry), vol. 50, pp. 239-242, 2002.
Huhn et al., “West Nile Virus in the United States: An Update on an Emerging Infectious Disease,”American Family Physician, vol. 68, No. 4, pp. 653-660, Aug. 15, 2003.
Johnson et al., “Detection of Anti-Arboviral Immunoglobulin G by Using a Monoclonal Antibody-Based Capture Enzyme-Linked Immunosorbent Assay,”Journal of Clinical Microbiology, vol. 38, No. 5, pp. 1827-1831, May 2000.
Johnson et al., “Duplex Microsphere-Based Immunoassay for Detection of Anti-West Nile Virus and Anti-St. Lois Encephalitis Virus Immunoglobulin M Antibodies,”Clinical and Diagnostic Laboratory Immunology, vol. 12, No. 5, pp. 566-574, May 2005.
Kellar et al., “Multiplexed Fluorescent Bead-Based Immunoassays for Quantitation of Human Cytokines in Serum and Culture Supernatants,”Cytometry, vol. 45, pp. 27-36, 2001.
Lindsey et al., “Serum Dilution Neutralization Test for California Group Virus Identification and Serology,”American Society for Biology, vol. 4, No. 6, pp. 503-510, 1976.
Martin et al., “Standardization of Immunoglobulin M Capture Enzyme-Linked Immunosorbent Assays for Routine Diagnosis of Arboviral Infections,”Journal of Clinical Microbiology, vol. 38, No. 5, pp. 1823-1826, May 2000.
Monath et al., “Immunoglobulin M Antibody Capture Enzyme-Linked Immunosorbent Assay for Diagnosis of St. Louis Encephalitis,”Journal of Clinical Microbiology, vol. 20, No. 4, pp. 784-790, Oct. 1984.
Mossman, “Three-way ROCs,”Medical Decision Making, vol. 19, No. 1, pp. 78-89, Jan.-Mar. 1999.
Mostashari et al., “Epidemic West Nile encephalitis, New York, 1999: results of a household-based seroepidemiological survey,”The Lancet, vol. 358, pp. 261-264, Jul. 2001.
Tardei et al., “Evaluation of Immunoglobulin M (IgM) and IgG Enzyme Immunoassays in Serologic Diagnosis of West Nile Virus Infections,”Journal of Clinical Microbiology, vol. 38, No. 6, pp. 2232-2239, Jun. 2000.
Wong et al., “Detection of Human Anti-Flavivirus Antibodies with a West Nile Virus Recombinant Antigen Microsphere Immunoassay,”Journal of Clinical Microbiology, vol. 42, No. 1, pp. 65-72, Jan. 2004.
Wong et al., “Immunoassay Targeting Nonstructural Protein 5 to Differentiate West Nile Virus Infection from Dengue and St. Louis Encephalitis Virus Infections and from Flavivirus Vaccination,”Journal of Clinical Microbiology, vol. 41, No. 9, pp. 4217-4223, Sep. 2003.
Jones et al., “Multiplex Assay for Detection of Strain-Specific Antibodies Against the Two Variable Regions of the G Protein of Respiratory Syncytial Virus,”Clinical and Diagnostic Laboratory Immunology, May 2002, (pp. 633-638).
Martins, “Development of Internal Controls for the Luminex Instrument as Part of a Multiplex Seven-Analyte Viral Respiratory Antibody Profile,”Clinical and Diagnostic Laboratory Immunology, Jan. 2002, (pp. 41-45).
Opalka et al., “Simultaneous Quantitation of Antibodies to Neutralizing Epitopes on Virus-Like Particles for Human Papillomavirus Types 6, 11, 16 and 18 by a Multiplexed Luminex Assay,”Clinical and Diagnostic Laboratory Immunology, Jan. 2003, (pp. 108-115).
Yan et al., “Microsphere-base duplexed immunoassay for influenza virus typing by flow cytometry,”Elsevier Journal of Immunology Methods, 2004, (pp. 27-38).
“Smaller Reagent Manufacturers Provide Their own Answers to Reagent Rental Contracts with New Ways to Cut Costs in the Clinical Laboratory Space,”Business Wire, 2 pages, Feb. 2004.
“U.S. Clinical Chemistry and Immunoassay Reagents Markets,” Frost & Sullivan, http://www.mindbranch.com/listing/product/R1-4176.html, 6 pages, Feb. 2004.
Johnson et al., “Duplex Microsphere-Based Immunoassay for Detection of Ant-West Nile Virus and Anti-St. Louis Encephalitis Virus Immunoglobin M Antibodies,”Clinical and Diagnostic Laboratory Immunology, vol. 12, No. 5, p. 566-574, May 2005.
Wong et al., “Immunoassay Targeting Nonstructural Protein 5 to Differentiate West Nile Virus Infection from Dengue and St. Louis Encephalitis Virus Infections and from Flavivirus Vaccination,”Journal of Clinical Microbiology, pp. 4217-4223, Sep. 2003.
“A Microsphere Immunofluorescence Assay which measures specific Virus Nonstructural Proteins in sera and spinal fluids,” Health Research, http://www.hrinet.org/techtran/technologies/westnile.htm, 2 pages, dated at least as early as Nov. 29, 2004.
“APHL,” Association of Public Health Laboratories, http://web.archive.org/web/20041128092409/http://www.aphl.org, 2 pages, web-archived on Nov. 28, 2004.
“Bayer Diagnostics—About Us,” Bayer HealthCare, http://web.archive.org/web/20040722015028/http://www.bayerdiag.com/aboutus.cfm, 1 page, web-archived on Jun. 6, 2004.
“Bioterrorism Detection,” Biohazard News, http://web.archive.org/web/20041012194128/http://bio
Biggerstaff Bradley John
Johnson Alison Jane
Klarquist & Sparkman, LLP
Smith Carolyn L.
The United States of America as represented by the Department of
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