Multiplex quantitative nucleic acid amplification and...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S091200

Reexamination Certificate

active

08039215

ABSTRACT:
The invention is a single-tube multiplex assay, capable of simultaneously amplifying, detecting and quantifying multiple nucleic acid targets, using multiple hybridization probes, labeled with the same fluorescent reporter label, but each having a distinct melting temperature. The assay can be further multiplexed with the use of multiple sets of hybridization probes, each set labeled with a separate fluorescent reporter label.

REFERENCES:
patent: 6140054 (2000-10-01), Wittwer et al.
patent: 6245514 (2001-06-01), Wittwer
patent: 6472156 (2002-10-01), Wittwer et al.
patent: 6569627 (2003-05-01), Wittwer et al.
patent: 7019129 (2006-03-01), Cook et al.
patent: 2004/0175752 (2004-09-01), Schaffer et al.
patent: 2005/0053950 (2005-03-01), Zudaire Ubani et al.
patent: 2006/0177841 (2006-08-01), Wangh et al.
patent: 1288314 (2003-03-01), None
patent: 1288314 (2004-02-01), None
patent: 1288314 (2006-08-01), None
patent: 10002350 (2010-07-01), None
patent: 0018965 (2000-04-01), None
patent: 2004074447 (2004-09-01), None
patent: 2004074447 (2004-09-01), None
patent: 2009042728 (2009-04-01), None
patent: 2009135832 (2009-11-01), None
Bell, Andrew S., et al., 2002, “Real-time quantitative PCR in parasitology”, Trends in Parasitology, 18(8):337-342.
Castro, Maria E., et al., 2008, “PPP1CA contributes to the senescence program induced by oncogenic Ras”, Carcinogenesis, 29(3):491-499.
De Silva, Deepika, et al., 1998, “Rapid Genotyping and Quantification on the LightCycler (TM) with Hybridization Probes”, Biochemica, 2:12-15.
Muller, Stefan, et al., 2001, “Sumo, Ubiquitin's Mysterious Cousin”, Nature Reviews/Molecular Cell Biology, 2:2002-210.
Ririe, Kirk M., et al., 1997, “Product Differentiation by Analysis of DNA Melting Curves during the Polymerase Chain Reaction”, Analytical Biochemistry, 245:154-160.
Sparano, Joseph A., et al., 2008, “Development of the 21-Gene Assay and Its Application in Clinical Practice and Clinical Trials”, Journal of Clinical Oncology, 26(6):721-728.
Wittwer, Carl T., et al., 2001, “Real-Time Multiplex PCR Assays”, Methods, 25:430-442.
Yeh, Edward T. H., et al., 2000, “Ubiquitin-like proteins: new wines in new bottles”, Gene, 248:1-14.
Longo, Mary C., et al., 1990, “Use of uracil DNA glycosylase to control carry-over contamination in polymerase chain reaction”, Gene, 93(1):125-128.
Szilvasi, Aniko, et al., 2005, “Asymmetric PCR increases efficiency of melting peak analysis on the LightCycler”, Clinical Biochemistry, 38(8):727-730.
Zhang, Xiuling, et al., 2004, “Development of a Real-Time Polymerase Chain Reaction-Based Method for the Measurement of Relative Allelic Expression and Identification of CYP2A13 Alleles with Decreased Expression in Human Lung”, 311(1):373-381.

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