Multiplex oligonucleotide addition and target amplification

Details Multiplex oligonucleotide addition and target amplification Multiplex oligonucleotide addition and target amplification

2007-04-24

2007-04-24

Martinell, James (Department: 1634)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

C435S091200

Reexamination Certificate

active

10300311

ABSTRACT:
Methods for appending oligonucleotides directly to nucleic acid templates, particularly to defined sites internal to single-stranded templates, are described. Appending first and second common priming sites to each of a plurality of templates of distinct sequence allows the subsequent stoichiometric amplification of a plurality of templates of distinct sequence.

REFERENCES:
patent: 4945051 (1990-07-01), Kikuchi et al.
patent: 5185243 (1993-02-01), Ullman et al.
patent: 5439793 (1995-08-01), Rose et al.
patent: 5491063 (1996-02-01), Fisher et al.
patent: 5508178 (1996-04-01), Rose et al.
patent: 5525494 (1996-06-01), Newton
patent: 5565340 (1996-10-01), Chenchik
patent: 5582989 (1996-12-01), Caskey et al.
patent: 5595891 (1997-01-01), Rose et al.
patent: 5612199 (1997-03-01), Western et al.
patent: 5728526 (1998-03-01), George, Jr. et al.
patent: 5731171 (1998-03-01), Bohlander
patent: 5851770 (1998-12-01), Babon et al.
patent: 5882856 (1999-03-01), Shuber
patent: 5888731 (1999-03-01), Yager et al.
patent: 5928905 (1999-07-01), Stemmer et al.
patent: 5952176 (1999-09-01), McCarthy et al.
patent: 6045994 (2000-04-01), Zabeau et al.
patent: 6117679 (2000-09-01), Stemmer
patent: 6130073 (2000-10-01), Eggerding
patent: 6150516 (2000-11-01), Brenner et al.
patent: 6207372 (2001-03-01), Shuber
patent: 6207424 (2001-03-01), Chou et al.
patent: 6326145 (2001-12-01), Whitcombe et al.
patent: 6350580 (2002-02-01), Sorge
patent: 6355422 (2002-03-01), Liu et al.
patent: 6361942 (2002-03-01), Coull et al.
patent: 6410278 (2002-06-01), Notomi et al.
patent: 2001/0049125 (2001-12-01), Stemmer et al.
patent: 2002/0102591 (2002-08-01), Sorge
patent: 2002/0119448 (2002-08-01), Sorge et al.
patent: 2002/0137036 (2002-09-01), Sorge et al.
patent: 2003/0104459 (2003-06-01), Faham et al.
patent: 2004/0224352 (2004-11-01), Fan et al.
patent: 0 799 897 (1997-10-01), None
patent: 0971 039 (2000-01-01), None
patent: 1020 534 (2000-05-01), None
patent: WO 96/33207 (1996-10-01), None
patent: WO 96/41012 (1996-12-01), None
patent: WO 97/45559 (1997-12-01), None
patent: WO 99/49293 (1999-09-01), None
patent: WO-99/66071 (1999-12-01), None
patent: WO 01/06012 (2001-01-01), None
patent: WO 01/32922 (2001-05-01), None
patent: WO 01/38556 (2001-05-01), None
patent: WO 01/94625 (2001-12-01), None
patent: WO 02/29112 (2002-04-01), None
patent: WO 02/36821 (2002-05-01), None
patent: WO 02/59354 (2002-08-01), None
patent: WO 02/59355 (2002-08-01), None
patent: WO 02/70751 (2002-09-01), None
Eurogenetic,Quantitative and Qualitative PCR Technology: All Types of Probes and Related Expertise in One Company: pp. 1-47 (2002).
http://www4.amershambiosciences.com/aptrix/upp01077.nsf/Content/gel—blot—fluor—imaging.html “Multiplex PCR Product Analysis: Increased Accuracy and Throughput.” (Oct. 31, 2002).
http://www.bu.edu/research/Features/sciocoalition—01/twist.html “A New Twist on a Powerful Theme.” (Oct. 31, 2002).
http://www.bu.edu/research/Features/sciocoalition—01/twist2.html “Return to a New Twist.” (Oct. 31, 2002).
http://www.dxsgenotyping.com/technology—main.htm “Sorpions™ Technology for PCR Analysis.” (Oct. 31, 2002).
http://www.eurogentec.be/code/en/thec—real—scor.htm “Scorpions™ Genomics Oligonucleotides Synthesis.” (Oct. 31, 2002).
http://www.info.med.yale.edu/genetics/ward/tavi/Guide.html “PCR and Multiplex PCR Guide.” (Oct. 31, 2002).
http://www.info.med.yale.edu/genetics/ward/tavi/p01.html “PCR Generalities.” (Oct. 31, 2002).
http://www.info. med.yale.edu/genetics/ward/tavi/p02.html “Choosing/Designing PCR Primers.” (Oct. 31, 2002.
http://www.info.med.yale.edu/genetics/ward/tavi/p04.html “Multiplexing Primer Pairs.” (Oct. 31, 2002).
http://www.mdlab.com/fees&servs/serv-polymerase.html “Medical Diagnostic Laboratories Diagnostic Services: Application of the Polymerase Chain Methodologies in Molecular Diagnostic Medicine.” (Oct. 31,, 2002).
http://www.medprobe.com
o/rtper.html “MedProbe: Real Time PCR Products and Instruments.” (Oct. 31, 2002).
http://www.qiagen.com/clinical/applications/technologies/multiplex—pcr.asp “Molecular Diagnostics Research and Clinical Research.” (Oct. 31, 2002).
Kebelmann-Betzing et al., “Advantages of a newTaqDNA Polymerase in Multiplex PCR and Time-Release PCR,”Biotechniquesvol. 24 No. 1: pp. 154-158 (1998).
Thelwell et al., “Mode of Action and Application of Scorpion Primers to Mutation Detection,”Nucleic Acids Researchvol. 28 No. 19: pp. 3752-3761 (2000).
Whitcombe et al., “Detection of PCR Products Using Self-Probing Amplicons and Fluorescense,”Nature Biotechnologyvol. 17: pp. 804-807 (Aug. 1999).
Zangenberg et al., “Improved Multiplex PCR of Plymorphic Markers,” http://www.promega.com/geneticidproc/ussymp7proc/ab73.html (Oct. 31, 2002).
Baskaran et al., “Uniform Amplification of a Mixture of Deoxyribonucleic Acids with Varying GC Content,”Genome Researchvol. 6 No. 7: pp. 633-638 (Jul. 1996).
Brookes et al., “Cloning the Shared Components of Complex DNA Resources,”Human Molecular Geneticsvol. 3 No. 11: pp. 2011-2017 (1994).
Broude et al., “Multiplex Allele-Specific Target Amplification Based on PCR Suppression,”Proclamation of the National Academy of Sciences of the USAvol. 98: pp. 206-211 (2001).
Chamberlain et al., “Deletion Screening of the Duchenne Muscular Dystrophy Locus via Multiplex DNA Amplification,”Nucleic Acids Researchvol. 16 No. 23: pp. 11141-11156 (1988).
Fan et al., “Parallel Genotyping of Human SNPs Using Generic High-Density Oligonucleotide Tag Arrays,”Genome Researchvol. 10: pp. 853-860 (2000).
Henegariu et al., “Multiplex PCR: Critical Parameters and Step-by-Step Protocol,”Biotechniquesvol. 23 No. 3: pp. 504-511 (1997).
Markoulatos et al., “Multiplex Polymerase Chain Reaction: A Practical Approach,”J. Clin. Lab. Anal.vol. 16: pp. 47-51 (2002).
Shoemaker et al., “Quantitative Phenotypic Analysis of Yeast Deletion Mutants Using a Highly Parallel Molecular Bar-Coding Strategy,”Nature Geneticsvol. 14 No. 4: pp. 450-456 (1996).
Tatusova et al., “Blast 2 Sequences—A New Tool for Comparing Protein and Nucleotide Sequences,”FEMS Microbiology Lettersvol. 174: pp. 247-250 (1999).
Brownie, J. et al. “The elimination of primer -dimer accumulation in PCR” Nuc. Acids Res., Oxford University Press, vol. 25, No. 16, 3235-3241 (1997).
Peale, F. et al. “Multiplex display polymerase chain reaction amplifies and resolves related sequences sharing a single moderately conserved domain” Anal Biochem. vol. 256, No. 2, 158-168, (1998).
Broude, N.E., “Stem-loop oligonucleotides: a robust tool for molecular biology and biotechnology,” Trends in Biotechnology, 20-6: 249-256, (2002).

Affiliated with

Also associated with

Rating

Multiplex oligonucleotide addition and target amplification does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Multiplex oligonucleotide addition and target amplification, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multiplex oligonucleotide addition and target amplification will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3777715