Multiplex data collection and analysis in bioanalyte detection

Details Multiplex data collection and analysis in bioanalyte detection Multiplex data collection and analysis in bioanalyte detection

2005-09-01

2008-08-12

Whisenant, Ethan (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S007100, C435S283100, C435S287200

Reexamination Certificate

active

07410763

ABSTRACT:
Method and device to collect multiplex data simultaneously in analyte detection and analyze the data by experimentally trained software (machine-learning) is disclosed. Various ways (magnetic particles and microcoils) are disclosed to collect multiple reporter (tag) signals. Multiplex detection can increase the biomolecule analysis efficiency by using small sample size and saving assay reagents and time. Machine learning and data analysis schemes are also disclosed. Multiple affinity binding partners, each labeled by a unique reporter, are contacted with a sample and a green spectrum is taken to detect multiple reporter signals. The spectrum is deconvoluted by experimentally trained software to identify multiple analytes.

REFERENCES:
patent: 4245171 (1981-01-01), Rabinowitz et al.
patent: 4444879 (1984-04-01), Foster et al.
patent: 5766963 (1998-06-01), Baldwin et al.
patent: 6514767 (2003-02-01), Natan
patent: 6861263 (2005-03-01), Natan
patent: 2002/0090662 (2002-07-01), Ralph
patent: 2003/0032035 (2003-02-01), Chatelain et al.
patent: 2003/0224457 (2003-12-01), Hurt et al.
patent: 2004/0053237 (2004-03-01), Liu et al.
patent: 2004/0142484 (2004-07-01), Berlin et al.
patent: 2004/0152200 (2004-08-01), Deshmukh
patent: 2005/0064435 (2005-03-01), Su et al.
patent: 2005/0064604 (2005-03-01), Bohmann et al.
patent: 2005/0123974 (2005-06-01), Gilmanshin et al.
patent: 2005/0130163 (2005-06-01), Smith et al.
patent: 2005/0147976 (2005-07-01), Su
patent: 2005/0147977 (2005-07-01), Koo et al.
patent: 2005/0151966 (2005-07-01), Packirisamy et al.
patent: 2005/0196876 (2005-09-01), Chan et al.
patent: 2006/0057576 (2006-03-01), Paszkowski et al.
patent: 2007/0117212 (2007-05-01), Kautz et al.
Su et al., Composite Organic-Inorganic Nanoparticles (COINs) with chemically encoded optical signatures. □□NANO Letters 5(1) : 49-54 (Jan. 2005).
Wang et al., Microarrays assembled in microfluidic chips fabricated from poly(methyl methacrylate) for the detection of low-abundant DNA mutations. Analytical Chemistry 75 : 1130-1140(2003).
Han, et al., “Quantum-Dot-Tagged Microbeads for Multiplexed Optical Coding of Biomolecules”, Nature Biotechnology, vol. 19, Jul. 2001 (pp. 631-635).
Non-Final Office Action (mailed Jul. 2, 2007), U.S. Appl. No. 11/026,857, filed Dec. 30, 2004, First Named Inventor: Xing Su (30 pages).
Non-Final Office Action (mailed Jun. 29, 2007), U.S. Appl. No. 11/027,470, filed Dec. 30, 2004, First Named Inventor: Mark Roth (25 pages).

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