Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2007-06-19
2007-06-19
Brumback, Brenda (Department: 1647)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C436S501000, C436S056000, C436S172000, C530S350000, C530S402000, C536S023500, C435S069100
Reexamination Certificate
active
10771853
ABSTRACT:
The present invention relates generally to molecular assemblies, more particularly to an assay for the detection of G-protein coupled receptor (GPCR) molecular assemblies and bead-based detection of ligand-GPCR complexes and to methods for identifying compounds as agonists, partial agonists or antagonists of the binding of G-protein coupled receptors to G-protein and for use of these compounds in the treatment of conditions or disease states in a mammalian subject or patient, including humans, where G-protein coupled receptor binding to G-protein is implicated.
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Biggs Sean
Cimino Daniel
Prossnitz Eric R.
Simons Peter
Sklar Larry A.
Brumback Brenda
Coleman Henry D.
Sapone William J.
Shafer Shulamith
STC.UNM
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