Multiple sclerosis associated polypeptide

Details Multiple sclerosis associated polypeptide Multiple sclerosis associated polypeptide

1996-10-28

1999-03-16

Hutzell, Paula K.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530353, 530361, 530380, 5303881, 53038815, 53038873, 53038875, 53038885, 530403, 530412, 530829, 530837, 530838, 530839, 4241841, 435 71, 435 724, C07K 14435, C07K 1600

Patent

active

058832270

ABSTRACT:
The present invention relates to the diagnosis of multiple sclerosis. More specifically, this invention relates to an assay for detecting antigen(s) associated with multiple sclerosis. The present invention also relates to the generation of hybridomas which produce monoclonal antibodies which are specific for the multiple sclerosis-associated antigens. The present invention's use is in diagnosing multiple sclerosis and in routine follow-up monitoring of multiple sclerosis patients as to disease progression or response to therapy.

REFERENCES:
patent: 3864481 (1975-02-01), Hashim
patent: 3929982 (1975-12-01), Coggins
patent: 3932601 (1976-01-01), Coggins
patent: 4113858 (1978-09-01), Hashim
patent: 4294818 (1981-10-01), McMichael et al.
patent: 4376110 (1983-03-01), David et al.
patent: 4486530 (1984-12-01), David et al.
patent: 4918163 (1990-04-01), Young et al.
Norton 1984 Ann. N.Y. Acad. Sci vol. 436, 5-10.
Current Protocols in Immunology editing by Coligan John, (1991, vol. 1, pp. 2.5.1, 2.5.2).

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