Multiple promoters and the use thereof for gene expression

Details Multiple promoters and the use thereof for gene expression Multiple promoters and the use thereof for gene expression

2011-06-28

2011-06-28

Qian, Celine X (Department: 1636)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S320100, C435S252300

Reexamination Certificate

active

07968699

ABSTRACT:
The present invention relates to multiple promoters and to expression units comprising them; to the use thereof for regulating transcription and expression of genes; to expression cassettes which comprise multiple promoters or expression units of this kind; to vectors which comprise such expression cassettes; to genetically modified microorganisms which comprise vectors and/or expression units of this kind; and to processes for preparing biosynthetic products by culturing said genetically modified microorganisms.

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patent: WO-2005/059144 (2005-06-01), None
Ivanov, I., et al., Expression of Human Alpha 1 Interferon Genes in Vectors Containing Tandemly Located Promoters Recognized by Two Different RNA Polymerases (Escherichia coliand T7), FEMS Microbiology Letters, 1993, vol. 108, pp. 231-236.
Follettie, M. T., et al., “Gene Structure and Expression of theCorynebacterium flavumN13ask-asdOperon”, Journal of Bacteriology, 1993, vol. 175, No. 13, pp. 4096-4103.
Murakami, Y., et al, “Construction of New Excretion Vectors: Two and Three Tandemly Located Promoters are Active for Extracellular Protein Production fromEscherichia coli”, Appl. Microbial. Biotechnol., 1989, vol. 30, pp. 619-623.
Kalinowski, J., et al., “The CompleteCorynebacterium glutamicumATCC 13032 Genome Sequence and its Impact on the Production of L-Aspartate-Derived Amino Acids and Vitamins”, Journal of Biotechnology, 2003, vol. 104, pp. 5-25.

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