Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1994-05-20
1996-06-11
Housel, James C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
356243, 356306, 356448, 385 12, 385129, 385130, 422 8205, 422 8208, 422 8211, 4352872, 4352879, 435808, 4352887, 436164, 436172, 436527, 436805, G01N 33552, G01N 368
Patent
active
055254667
ABSTRACT:
An evanescent wave system and method including an optical sensor for use in assaying a reference material and at least one molecular species or analyte in a test medium or test sample for diagnostic and other applicable purposes. The sensor includes a waveguide for propagating a radiation input along its length. The radiation input causes evanescent electromagnetic waves that are capable of stimulating output emissions that are indicative of a reference material and of one or more molecular species or analytes. By comparing the emission(s) indicative of the reference material to the emission indicative of the presence of the molecular species or analyte, the presence and concentration of the molecule in the sample can be determined. The reference material provides for normalization and/or calibration of the system.
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Stewart, G. et al. Referencing Systems for Evanescent Wave Sensors. Proc. of SPIE (1990) 1314; 262-269.
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Cook Thomas A.
Love Walter F.
Schulkind Richard L.
Slovacek Rudolf E.
Walczak Irene M.
Chin Christopher L.
Ciba Corning Diagnostics Corp.
Housel James C.
Morgenstern Arthur S.
Roesler Judith A.
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