Multiple oligonucleotide containing oligomers and the cleanable

Details Multiple oligonucleotide containing oligomers and the cleanable Multiple oligonucleotide containing oligomers and the cleanable

1994-11-07

1996-09-03

Robinson, Douglas W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 2531, 536 2533, 536 2534, 536 255, 536 256, 536 253, 548413, 549 6, 549222, 558180, 558179, C07H 2100, C07F 902, C07D33300, C07C 6966

Patent

active

055525350

ABSTRACT:
A method for the synthesis of a plurality of oligonucleotides comprising the steps of

REFERENCES:
patent: 4775619 (1988-10-01), Urdea
patent: 5118605 (1992-06-01), Urdea
patent: 5380833 (1995-01-01), Urdea
patent: 5393877 (1995-04-01), McLean et al.
Agarwal et al., "Studies on Polynucleotides. CXLIII. A Rapid and Convenient Method for the Synthesis of Deoxyribooligonucleotides Carrying 5'-Phosphate End Groups Using a New Protecting Group," J. Am. Chem. Soc., 98(5), 1065-1072 (1976).
Brandstetter et al., "Neue Polymer-Schutzgruppe in der Oligonucleotidsyntheses, 2-Hydroxyathylphenylthioather von Polyathyleneglykol", Tett. Lett., 1974(31), 2705-2708.
Ikehara et al., "The Synthesis of Polynucleotides," Adv. Carbohydrate Chem. Biochem., 36, 135-213 (1979); only pp. 135 and 204-213 supplied.

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