Multiple micro-arrays

Details Multiple micro-arrays Multiple micro-arrays

1999-10-07

2000-10-24

Jones, W. Gary

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

4352872, 435 6, 422 50, 422 58, C12M 300, C12Q 168, G01N 2100

Patent

active

061365920

ABSTRACT:
A method and device are provided for simultaneously creating a plurality of identical micro-arrays of biological samples. The invention utilizes a plurality of substrates, each of which having a top side, a bottom side, and a pattern of through-holes. Each through-hole has a wider upper cross-section, a narrower lower cross-section, and a step or plateau formed in the transition area. When the substrates are stacked, through-holes are in registry and form tunnels extending through the stack of substrates. Reagents of interest are caused to flow through the tunnels and deposit on the step or plateau area. A barrier layer may be provided to prevent leak-through between neighboring holes. After the desired reagents have been deposited, the substrates are separated. In this manner a series of micro-arrays, each capable of containing hundreds or thousands of biological samples such as cDNA fragments, is formed simultaneously.

REFERENCES:
patent: 5486335 (1996-01-01), Wilding et al.
patent: 5744366 (1998-04-01), Kricka et al.
patent: 5800992 (1998-09-01), Fodor et al.

Affiliated with

Also associated with

Rating

Multiple micro-arrays does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Multiple micro-arrays, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multiple micro-arrays will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1962437