Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;... – Enzyme or microbial cell is immobilized on or in an organic...
Patent
1988-07-12
1990-07-17
Warden, Robert J.
Chemistry: molecular biology and microbiology
Carrier-bound or immobilized enzyme or microbial cell;...
Enzyme or microbial cell is immobilized on or in an organic...
435174, 43524022, C12N 1104
Patent
active
049421298
ABSTRACT:
Living tissues, such as hybridoma cells or insect cells suspended in a water soluble gelling agent, are microencapsulated in a double polymeric membrane microcapsule. The inner membrane is of a high molecular weight cut-off to permit outward diffusion of the gelling agent and also expansion of the microcapsule before formation of the outer membrane which is a relatively lower molecular weight cut-off. The living cells in the dual membrane microcapsule may be grown to an intracapsular density which is significantly higher than that which can be achieved by using single-membrane capsules. The recovery of intracapsular protein product (produced by the encapsulated cells) is also significantly higher and the loss of product through the membrane wall markedly lower for the dual membrane capsule than for the single membrane capsule.
REFERENCES:
patent: 4251387 (1981-02-01), Lim et al.
patent: 4257884 (1981-03-01), Lim
patent: 4352883 (1982-10-01), Lim
patent: 4391909 (1983-07-01), Lim
patent: 4407957 (1983-10-01), Lim
patent: 4409331 (1983-10-01), Lim
patent: 4495288 (1985-01-01), Jarvis, Jr. et al.
patent: 4582799 (1986-04-01), Jarvis, Jr.
patent: 4778749 (1988-10-01), Vasington et al.
patent: 4803168 (1989-02-01), Jarvis, Jr.
Daugulis Andrew J.
Faulkner Peter
Goosen Matheus F. A.
King Glenn A.
Hicks Richard J.
McMahon Timothy M.
Queen's University at Kingston
Warden Robert J.
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