Multiple laminar flow-based rate zonal or isopycnic...

Details Multiple laminar flow-based rate zonal or isopycnic... Multiple laminar flow-based rate zonal or isopycnic...

2006-12-19

2006-12-19

Nguyen, Kiet T. (Department: 2881)

Liquid purification or separation

Processes

Making an insoluble substance or accreting suspended...

C210S800000, C210S802000, C210S924000, C435S173100, C422S072000, C422S082050, C422S105000, C436S177000

Reexamination Certificate

active

07150834

ABSTRACT:
The invention provides a method and apparatus for separating blood into components, may be expanded to include other types of cellular components, and can be combined with holographic optical manipulation or other forms of optical tweezing. One of the exemplary methods includes providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.

REFERENCES:
patent: 4409106 (1983-10-01), Furuta et al.
patent: 4424132 (1984-01-01), Iriguchi
patent: 6815664 (2004-11-01), Wang et al.
patent: 6833542 (2004-12-01), Wang et al.

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