Multiple injection analysis

Chemistry: analytical and immunological testing – Automated chemical analysis – With a continuously flowing sample or carrier stream

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436 63, 436150, 436174, 436179, 436180, 436807, 422 81, 422 8201, 422 8202, 422 8212, 7386421, 7386371, G01N 3508

Patent

active

057417091

ABSTRACT:
An apparatus for flow injection analysis is disclosed which comprises: (a) an open flow cell containing an upper cell body, a lower cell body contiguously affixed to the upper cell body, and a cell chamber provided in the upper cell body, the cell chamber having a bottom and a top, wherein the top of the cell chamber is open to an atmosphere; (b) a carrier fluid inlet port provided in a lower portion of the upper cell body and in communication with the cell chamber; (c) a fluid delivery device for introducing a carrier fluid into the cell chamber through the carrier fluid inlet; (d) an over-flow outlet setup in an upper portion of the upper cell body to allow exit of the carrier fluid and thus maintaining a constant fluid volume in the cell chamber; (e) a detector disposed in the lower cell body in such a manner that its detecting surface is placed at the bottom of the cell chamber and and facing upward; and (f) a sample injecting assembly, separated from the inlet port and the fluid delivery device for injecting a sample to be analyzed directly onto the detecting surface of the detector without requiring the carrier fluid to carry the sample to the cell chamber. The flow injection analysis disclosed in the present invention combines the advantages of both FIA (continuous operation) and BIA (no dilution by carrier solvent), while eliminating the disadvantages thereof.

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