Multiple gene transcription activity assay system

Details Multiple gene transcription activity assay system Multiple gene transcription activity assay system

2004-04-30

2009-08-11

Prouty, Rebecca (Department: 1652)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S320100, C536S023200

Reexamination Certificate

active

07572629

ABSTRACT:
A gene construct incorporating any of at least two luciferase genes which emit lights with different colors using an identical substrate such that the gene can be stably expressed in mammalian cells.

REFERENCES:
patent: 6387675 (2002-05-01), Wood et al.
patent: 6495355 (2002-12-01), Contag et al.
patent: 7276363 (2007-10-01), Viviani et al.
patent: 2002/0119542 (2002-08-01), Viviani et al.
patent: 2006/0265137 (2006-11-01), Zock et al.
patent: 2008/0090291 (2008-04-01), Wood et al.
patent: 2002-542791 (2002-12-01), None
patent: WO 97/24460 (1997-07-01), None
patent: WO 97/24490 (1997-07-01), None
patent: WO 98/10059 (1998-03-01), None
patent: WO 00/65076 (2000-11-01), None
patent: WO 00/79264 (2000-12-01), None
patent: WO 03/016839 (2003-02-01), None
Viviani, V.R. et al. (1999) “Cloning, sequence analysis, and expression of active phrixothrix railroad-worms luciferases: relationship between bioluminescence spectra and primary structures” Biochemistry 38:8271-8279.
Ohmiya, Y. et al. (2000) “Comparative aspects of a luciferase molecule from the Japanese luminous beetle, Rhagophthalmus ohbai” Sci. Rept. Yokosuka City Mus., 47:31-38.
Sumiya, M et al. (1999) “Cloning and expression of a luciferase from the Japanese luminous beetle Rhagophthalmus ohbai” Biolumin. Chemilumin., Proc. Int. Symp., pp. 433-436.
Grentzmann, G. et al., (1998) “A dual-luciferase reporter system for studying recoding signals” RNA 4:479-486.
Omiha K. et al. (2004) “Basic and application principle on the bioluminescence system of insect luciferases” The Japanese Biochemical Society, Tokyo, 76:5-15.
Nieuwehnuijsen, B.W. et al. (2003) “A dual luciferase multiplexed high-throughput screening platform for protein-protein interactions” J. Biomol. Screen. 8:676-684.
Viviani, V. (2001) “Thr226 is a key residue for bioluminescence spectra determination in beetle luciferases” Biochemical and Biophysical Research Communications 280:1286-1291.
Contag, P.R. et al. (1998) “Bioluminescent indicators in living mammals” Nature Medicine 4:245-247.
Thompson, E.M. et al. (1995) “Real time imaging of transcriptional activity in live mouse preimplantation embryos using a secreted luciferase” PNAS USA 92:1317-1321.
Dilella, A.G. et al. (1988) “Utility of firefly luciferase as a reporter gene for promoter activity in transgenic mice” Nucleic Acids Research 16:4159.
Supplemental Partial European Search Report from corresponding European patent application No. EP 04 73 0717, dated Oct. 10, 2007.
EBI Accession No. ABK90990, “Phrixotrix hirtusred light emitting luciferase, phRE, cDNA”, Nov. 2002.
EBI Accession No. Q9U4U7, “Phrixotrix hirtusred bioluminescence eliciting luciferase”, May 2000.
EBI Accession No. ABG31952, “Phrixotrix hirtusred light emitting luciferase, phRE, protein”, Nov. 2002.
Barry, J.K. and Miller, W.A. 2002 “A-1 ribosomal frameshift element that requires base pairing across four kilobases suggests a mechanism of regulating ribosome and replicase traffic on a viral RNA”Proc Natl Acad Sci USA99:11133-11138.
Kitayama, A. et al. 2003 “Creation of thermostable firefly luciferase with pH-insensitive luminescent color”Phytochemistry and Photobiology77:333-338.
Sohaskey, C.D. et al. 1992 “Construction and application of plasmid-and transposon-based promoter-probe vectors forStreptomyces spp. that employ aVibrio harveyiluciferase reporter cassette”J Bacteriol174:367-376.
Viviani, V.R. et al. 2002 “The influence of Ala243 (Gly247), Arg215 and Thr226 (Asn230) on the bioluminescence spectra and pH-sensitivity of railroad worm, click beetle and firefly luciferases”Phytochemistry and Photobiology76:538-544.
Wood, K.V. et al. 1989 “Introduction to beetle luciferases and their applications”J Bioluminescence and Chemiluminescence4:289-301.
Wood, K.V. et al. 1989 “Complementary DNA coding click beetle luciferases can elicit bioluminescence of different colors”Science244:700-702.
Zhang, J. et al. 2002 “Identification of human uroplakin II promoter and its use in the construction of CG8840, a urothelium-specific adenovirus variant that eliminates established bladder tumors in combination with docetaxel”Cancer Res62:3743-3750.

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