Multiple emulsions and methods of preparation

Details Multiple emulsions and methods of preparation Multiple emulsions and methods of preparation

1994-08-16

1997-04-22

Lovering, Richard D.

Compositions

Inorganic luminescent compositions

Tungsten containing

252312, 252314, 514941, B01J 1300

Patent

active

056226497

ABSTRACT:
Water-in-oil and water-n-oil-in-water multiple emulsions and methods of preparation employing polyoxyethylene polyoxypropylene block copolymers added to the inner aqueous phase during preparation of said emulsions. The emulsions are useful in numerous applications including, but not limited to, vaccine adjuvants, pharmaceuticals, cosmetics, foods, and various household and industrial uses.

REFERENCES:
patent: Re29909 (1979-02-01), Kurtz
patent: Re33210 (1990-05-01), Stoufer
patent: 2674619 (1954-04-01), Lundsted
patent: 2854378 (1958-09-01), Buckwalter
patent: 2979528 (1961-04-01), Lundsted
patent: 3022335 (1962-02-01), Lundsted
patent: 3036118 (1962-05-01), Jackson et al.
patent: 3089818 (1963-05-01), Stone
patent: 3140232 (1964-07-01), Noseworthy
patent: 3206410 (1965-09-01), M oller et al.
patent: 3228834 (1966-01-01), Gans et al.
patent: 3234143 (1966-02-01), Waldmann
patent: 3255108 (1966-06-01), Wiese
patent: 3311561 (1967-03-01), Anderson et al.
patent: 3355394 (1967-11-01), Korbanka et al.
patent: 3422842 (1969-01-01), Erickson
patent: 3450502 (1969-06-01), Hymes
patent: 3489690 (1970-01-01), Lachampt et al.
patent: 3565817 (1971-02-01), Lissant
patent: 3577522 (1971-05-01), Hymes
patent: 3590125 (1971-06-01), Hymes
patent: 3641240 (1972-02-01), Hymes et al.
patent: 3728777 (1973-04-01), Foley
patent: 3740421 (1973-06-01), Schmolka
patent: 3776857 (1973-12-01), Lindner
patent: 3826771 (1974-07-01), Anderson et al.
patent: 3846546 (1974-11-01), Lachampt et al.
patent: 3867521 (1975-02-01), Miskel et al.
patent: 3867533 (1975-02-01), Schmolka
patent: 3926840 (1975-12-01), Wendler et al.
patent: 3956259 (1976-05-01), Garcia et al.
patent: 3957969 (1976-05-01), Fujiyama et al.
patent: 4009117 (1977-02-01), Newingham et al.
patent: 4026817 (1977-05-01), Ciuti et al.
patent: 4035513 (1977-07-01), Kumano
patent: 4073886 (1978-02-01), Kehm
patent: 4100271 (1978-07-01), Krezanoski
patent: 4102807 (1978-07-01), Iwama et al.
patent: 4115548 (1978-09-01), Marsh et al.
patent: 4122029 (1978-10-01), Gee et al.
patent: 4125603 (1978-11-01), Audibert et al.
patent: 4184978 (1980-01-01), France et al.
patent: 4252793 (1981-02-01), Altman
patent: 4323560 (1982-04-01), Baschang et al.
patent: 4350605 (1982-09-01), Hughett
patent: 4360448 (1982-11-01), Li et al.
patent: 4371447 (1983-02-01), Webb et al.
patent: 4384974 (1983-05-01), Guthauser
patent: 4385049 (1983-05-01), Cuca
patent: 4395393 (1983-07-01), Schmolka
patent: 4407790 (1983-10-01), Oakes et al.
patent: 4409209 (1983-10-01), Baschang et al.
patent: 4410660 (1983-10-01), Straus
patent: 4422952 (1983-12-01), Koulhanis et al.
patent: 4446044 (1984-05-01), Rutkiewic et al.
patent: 4446051 (1984-05-01), Berthod et al.
patent: 4474912 (1984-10-01), Ozmeral et al.
patent: 4489158 (1984-12-01), Straus
patent: 4562214 (1985-12-01), Barker et al.
patent: 4575484 (1986-03-01), Straus
patent: 4592859 (1986-06-01), Smith-Johannsen
patent: 4606918 (1986-08-01), Allison et al.
patent: 4609546 (1986-09-01), Hiratani
patent: 4690774 (1987-09-01), Vishnupad et al.
patent: 4698178 (1987-10-01), Huttinger et al.
patent: 4707470 (1987-11-01), Kirsh et al.
patent: 4708753 (1987-11-01), Forsberg
patent: 4720353 (1988-01-01), Bell
patent: 4793826 (1988-12-01), Hayes et al.
patent: 4801452 (1989-01-01), Hunter et al.
patent: 4808334 (1989-02-01), Ezaki et al.
patent: 4837014 (1989-06-01), Hunter et al.
patent: 4837083 (1989-06-01), Hunter et al.
patent: 4851220 (1989-07-01), Yim et al.
patent: 4879109 (1989-11-01), Hunter
patent: 4880563 (1989-11-01), Dahms
patent: 4897263 (1990-01-01), Hunter
patent: 4931210 (1990-06-01), Takahashi et al.
patent: 4933179 (1990-06-01), Allison et al.
patent: 4937070 (1990-06-01), Hunter
patent: 4940577 (1990-07-01), Greenberg et al.
patent: 4943390 (1990-07-01), Hayes et al.
patent: 4960814 (1990-10-01), Wu et al.
patent: 4971721 (1990-11-01), Takahashi et al.
patent: 4980084 (1990-12-01), Vishnupad et al.
patent: 4985173 (1991-01-01), Takahashi et al.
patent: 4985250 (1991-01-01), Bee et al.
patent: 4988456 (1991-01-01), Takahashi et al.
patent: 4997644 (1991-03-01), Hunter
patent: 5017370 (1991-05-01), Hunter et al.
patent: 5028599 (1991-07-01), Hunter
patent: 5030448 (1991-07-01), Hunter
patent: 5032394 (1991-07-01), Hunter
patent: 5037653 (1991-08-01), Dawson
patent: 5039520 (1991-08-01), Hunter
patent: 5041288 (1991-08-01), Hunter
patent: 5047236 (1991-09-01), Hunter et al.
patent: 5061688 (1991-10-01), Beissinger et al.
patent: 5064643 (1991-11-01), Hunter et al.
patent: 5071649 (1991-12-01), Hunter
patent: 5078995 (1992-01-01), Hunter et al.
patent: 5080894 (1992-01-01), Hunter et al.
patent: 5089260 (1992-02-01), Hunter et al.
patent: 5114708 (1992-05-01), Hunter et al.
patent: 5250294 (1993-10-01), Hunter et al.
Hackh's Chemical Dictionary, McGraw-Hill, Inc., p. 431 (1972).
Hunter et al., "The Adjuvant Activity of Nonionic Block Polymer Surfactants. II. Antibody Formation and Inflammation Related to the Structure of Triblock and Octablock Copolymers," Journal of Immunology, vol. 133, No. 6, pp. 3167-3175 (1984).
Hunter et al., "Adjuvant Activity of Nonionic Block Copolymers. IV. Effect of Molecular Weight and Formulation of Titre and Isotype of Antibody," Vaccine, vol. 9, No. 4, pp. 250-256 (Apr., 1991).
Becher, Paul ed., Encyclopedia of Emulsion Technology, vol. 2, pp. 159-238 (1985).
Becher, P., "Macroemulsions", Nonionic Surfactants Physical Chemistry, Martin J. Schick, ed., Marcel Decker, pp. 435-492 (1987).
Schulman, JH, et al., "Molecular interactions at oil/water interfaces, Part I. Molecular complex formation and stability of oil in water emulsions", Trans. Faraday Soc., vol. 36, pp. 651-668 (1940).
Marshall, L., "HLB of nonionic surfactants: PIT and EIP methods", Nonionic Surfactants Physical Chemistry, Martin J. Schick, ed., Marcel Decker, New York, pp. 493-548 (1987).
Matsumoto, S., "W/O/W-type multiple emulsions", Nonionic Surfact ants Physical Chemistry, Martin J. Schick, ed., Marcel Decker, New York, pp. 549-600 (1987).
Hilleman, MR, et al., "The clinical preparation of adjuvant 65", Annals of Allergy, vol. 30, pp. 152-158 (1972).
Francis, DP, et al., Ann. Intern. Med., vol. 97, p. 362-366 (1982).
Schmolka, I., "A Review Of Block Polymer Surfactants," Journal of the American Oil Chemists Society, 54, No. 3, pp. 110-116 (1977).
Block and Graft Copolymerization, vol. 2, ed. by R. J. Ceresa, John Wiley & Sons, pp. 174-271 (1976).
Moore, A.R., et al, "Reduction Of Splenic Vascular Resistance During Profusion By Pluronic.RTM. F-68," Journal of Surgical Research, vol. 8, pp. 563-56 (1968).
Snippe, H. et al., "Adjuvant Effect of Nonionic Block Polymer Surfactants in Humoral and Cellular Immunity," Int. Archs Allergy appl. Immun., vol. 65, pp. 390-398 (1981).
Byars, N.E. et al., "Adjuvant formulation for use in vaccines to elicit both cell-mediated and humoral immunity" Vaccine, vol. 5, pp. 223-228 (Sep. 1987).
Paton, B.. et al. "The use of a nonionic detergent added to organ perfusates," Organ Perfusion and Preservation, ed. by Norman, J.C., Appleton-Century-Crofts, pp. 105-120 (1968).
Hunter, R.L. et al., "Nonionic Block Copolymer Surfactants as Immunological Adjuvants: Mecanisms of Action and Novel Formulations," Immunologcial Adjuvants and Vaccines, ed. by Gregoriadis, G. et al., Plenum Publishing Corp., pp. 133-144 (1989).
Hunter, R.L. et al., "The Adjuvant Activity of Nonionic Block Polymer Surfactants. I. The Role of Hydrophile-Lipophile Balance." J. Immun., vol. 127, No. 3 (1981).
Hunter, R.L. et al., "The Adjuvant Activity of Nonionic Block Polymer Surfactants. III. Characterization of Selected Biologically Active Surfaces," Scand. J. Immunol., vol. 23, pp. 287-300 (1986).
Hunter R. L.et al., "Adjuvant activity of non-ionic block copolymers. IV. Effect of molecular weight and formulation on titre and isotype of antibody." Vaccine, vol. 9, pp. 250-256 (Apr. 1991).
Takayama K. et al., "Adjuvant activity of non-ionic block copolymers. V. Modulation of antibody isotype by lipopolysaccharides. lipid A and precursors," Vaccine, vol. 9, pp. 257-265 (Apr. 1991).
Ketchum, L.D., et al. "Experimental Use

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