Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-12-23
1999-07-27
Caputa, Anthony C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 43525233, 4353201, 435325, 435362, 435365, 435367, 435 731, 43525411, 43525421, 4352541, 435 693, 536 231, 536 2374, 424 932, 424 935, 530823, C12P 2106, C12N 120, C12N 1500, C12N 506
Patent
active
059288981
ABSTRACT:
The invention provides isolated nucleic acid compounds encoding a multiple drug resistance protein of Aspergillus nidulans. Vectors and transformed host cells comprising the multiple drug resistance-encoding DNA of Aspergillus nidulans atrD are also provided. The invention further provides assays which utilize these transformed host cells.
REFERENCES:
G. Del Sorbo, et al. "Multidrug resistance in Aspergillus nidulans involves novel ATP-binding cassette transporters." Mol. Gen. Genet. 254:417-426 (1997).
M. B. Tobin, et al. "Genes encoding multiple drug resistance-like proteins in Aspergillus fumigatus and Aspergillus flavus." Gene 200:11-23 (1997).
S. J. Thornewell, et al. "Cloning and characterization of CneMDR1: a Cryptococcus neoformans gene encoding a protein related to multidrug resistance proteins." Gene 201:21-29 (1997).
Xuei et al, Current Genetics 26: 225-227, 1994.
Hodges et al, Journal of Industrial Microbiology 13: 372-381, 1994.
Mackey et al., Analytical Biochemistry 212: 428-435, 1993.
Andrade Alan C.
de Waard Maarten A.
Peery Robert Brown
Skatrud Paul Luther
Caputa Anthony C.
Eli Lilly and Company
Weatherspoon John K.
Webster Thomas D.
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