Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1997-12-23
1999-08-31
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
4352523, 43525411, 4353201, 435325, 435410, 435455, 435468, 435471, 536 232, C12N 916, C12N 1500, C12N 120, C07H 2104
Patent
active
059453249
ABSTRACT:
The invention provides isolated nucleic acid compounds encoding a multiple drug resistance protein of Aspergillus nidulans. Vectors and transformed host cells comprising the multiple drug resistance-encoding DNA of Aspergillus nidulans atrC are also provided. The invention further provides assays which utilize these transformed host cells.
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G. Del Sorbo, et al. "Multidrug resistance in Aspergillus nidulans involves novel ATP-binding cassette transporters." Mol. Gen. Genet. 254:417-426 (1997).
M. B. Tobin, et al. "Genes encoding multiple drug resistance-like proteins in Aspergillus fumigatus and Aspergillus flavus." Gene 200:11-23 (1997).
S. J. Thornewell, et al. "Cloning and characterization of CneMDRI: a Cryptococcus neoformans gene encoding a protein related to multidrug resistance proteins." Gene 201:21-29 (1997).
Andrade Alan C.
de Waard Maarten A.
Peery Robert Brown
Skatrud Paul Luther
Eli Lilly and Company
Stole Einar
Wax Robert A.
Webster Thomas D.
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