Multiple capture probe sandwich assays

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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Details

435 912, C12Q 168, C12P 1934

Patent

active

056291566

ABSTRACT:
New methods for performing sandwich assays have been discovered. The assays utilize dual capture probes and eliminate noise resulting from nonspecific binding of detector probe to capture probe.

REFERENCES:
patent: 5015569 (1991-05-01), Pontins
Pritchard et al. Amplified detection of viral nucleic acid at subattomole levels using Q beta replicase. Ann. Biol. Clin. (Paris) (1990) 48:492-497. Abstract. 1988.
Stratagene Catalog, p. 39.
Morrissey, D.V. et al. Nucleic Acid Hybridization Assays Employing dA-Tailed Capture Probes I. Multiple Capture Methods. Anal. Biochem. (1989) 181: 345-359.

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