Multiple assay machine and method

Details Multiple assay machine and method Multiple assay machine and method

1976-07-26

1978-05-02

Serwin, R.E.

Chemistry: physical processes

Physical processes

Crystallization

232306, 23253R, 23259, 424 1, 424 15, G01N 3316, G01N 2310

Patent

active

040872483

ABSTRACT:
Method and apparatus are provided for carrying out simultaneous multiple manipulations. The method and apparatus are particularly directed toward heterogeneous (two phases) immunoassays, particularly radioimmunoassay (RIA) and immunoradiometricassays (IRMA and 2-site IRMA). These assays are primarily concerned with the determination of antibodies and immunologically active compounds (antigens and haptens). The device has a plurality of syringes mounted so as to allow for simultaneous and identical movement of the syringe plungers. In addition, means are provided for mounting open tubes, which are employed as solid phase reagents, to the ends of the syringes for the aspiration and discharge of unknown samples, reagents and wash solutions. A reservoir is provided in an upper portion of the apparatus for receiving solutions or dispensing solutions to the syringes. Individual assays may be carried out by using a single syringe and carrying out the process steps by transfers of solutions through a hollow tube.

REFERENCES:
patent: 3754863 (1973-08-01), Reunanen
patent: 3832135 (1974-08-01), Drozdowski et al.
patent: 3951605 (1976-04-01), Natelson

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