Multiple antigen peptide system

Details Multiple antigen peptide system Multiple antigen peptide system

1990-12-20

1993-07-20

Nucker, Christine M.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

530325, 530323, 530326, 530327, 530328, 530345, 530403, 530405, 530409, 424 88, 424 89, 424 92, 930 30, 930210, 930221, C07K 702, C07K 708, C07K 710, A61K 39385

Patent

active

052294900

ABSTRACT:
Multiple antigen peptide systems are described in which a large number of antigens are bound to the functional groups of a dendritic core molecule providing a high concentration of antigen in a low molecular volume. The products are useful for producing chemically defined univalent or multivalent vaccines and in diagnostic tests.

REFERENCES:
patent: 4289872 (1981-09-01), Deukewalter et al.
patent: 4515920 (1985-05-01), Erickson
patent: 4707357 (1987-11-01), Dame et al.
patent: 4713366 (1987-12-01), Stevens
Aharoni et al. (1982) Macromolecules 15:1093-1098.
Mitchell et al. (1982) in Monoclonal Hybridoma Antibodis CRC Press, Inc., Boca Raton, Fl. pp. 151-168.
Posnett et al. (1988) JBC 263(4):1719-1725.
Auriault et al. (1991) Peptide Res. 4(1):6-11.

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