Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1994-04-08
1998-10-06
Houtteman, Scott W.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 2432, C07H 2104
Patent
active
058177930
ABSTRACT:
An isolated and cloned region of a bacterial chromosome containing a multiple antibiotic resistance operon is disclosed. A description of the structure and function of the operon is provided as are assorted recombinant DNA constructs involving the operon or fragments thereof. The diagnostic, therapeutic and experimental uses of these constructs are also disclosed. Methods of evaluating the antibiotic effectiveness of compositions are disclosed and methods of treatment employing effective compositions are provided.
REFERENCES:
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George, A. et al., Amplifiable Resistance to Tetracycline, Chloramphenicol, and Other Antibiotics in Escherichia coli: Involvement of a Non-Plasmid-Determined Efflux of Tetracycline, J. of Bacteriology, vol. 155, No. 2, Aug. 1983, pp. 531-540.
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Houtteman Scott W.
Trustees of Tufts College
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