Multilayered controlled release pharmaceutical dosage form

Details Multilayered controlled release pharmaceutical dosage form Multilayered controlled release pharmaceutical dosage form

1995-12-07

1997-07-08

Hulina, Amy

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424490, 424494, 424497, 424458, 424461, 424472, A61K 936

Patent

active

056458584

ABSTRACT:
This invention is directed to a multilayered controlled release pharmaceutical dosage form. More particularly the dosage form is adapted for water soluble drugs and comprises a plurality of coated particles wherein each has multiple layers about a core containing a drug active whereby the drug containing core and at least one other layer of drug active is overcoated with a controlled release barrier layer and preferably an outer layer of additional drug is adapted for immediate release to preferably provide one immediate releasing layer and at least two controlled releasing layers of a water soluble drug from the multilayered coated particle.

REFERENCES:
patent: 5213811 (1993-05-01), Frisbee et al.
patent: 5229135 (1993-07-01), Philippon et al.
patent: 5320853 (1994-06-01), Noda et al.
patent: 5395626 (1995-03-01), Kotwal et al.
patent: 5407686 (1995-04-01), Patel et al.
patent: 5474786 (1995-12-01), Kotwal et al.

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