Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1984-07-20
1987-05-26
Kepplinger, Esther M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435805, 436501, 436518, 436531, 436535, 436810, 436817, 422 56, 422 57, G01N 33543, G01N 33545, G01N 33566
Patent
active
046686193
ABSTRACT:
A homogeneous specific binding assay device, a method for its preparation, and a method for its use in determining a ligand, such as antigen, hapten, or antibody, in, or the ligand binding capacity of, a liquid sample. The test device comprises a solid carrier member, such as a fibrous web matrix, e.g., paper, or a polymeric film or gel, incorporated with reagents for a homogeneous specific binding assay system which produces a detectable response, usually an electromagnetic radiation signal, that is a function of the presence or amount of the ligand in or the ligand binding capacity of the sample. Useful homogeneous specific binding assay systems include those involving enzyme substrate labels, enzyme prosthetic group labels, and enzyme labels. The detectable response preferably is a luminescent, fluorescent, spectrophotometric, or colorimetric response, which is measurable by visual observation or instrument means.
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patent: 4016043 (1977-04-01), Schuurs et al.
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patent: 4442204 (1984-04-01), Greenquist
patent: 4447529 (1984-05-01), Greenquist et al.
patent: 4461829 (1984-07-01), Greenquist
Greenquist Alfred C.
Li Thomas M.
Rupchock Patricia A.
Tyhach Richard J.
Walter Bert
Kepplinger Esther M.
Klawitter Andrew L.
Miles Laboratories Inc.
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