Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues
Reexamination Certificate
2006-10-25
2009-06-23
Tsang, Cecilia (Department: 1654)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Reexamination Certificate
active
07550557
ABSTRACT:
Disclosed herein are multilayer films comprising two or more layers of polyelectrolytes, wherein adjacent layers comprise oppositely charged polyelectrolytes. A first layer polypeptide comprising one or more first amino acid sequence motifs, wherein the one or more first amino acid sequence motifs has a length of 5 to 15 amino acids residues, and wherein the balance of charge in the first amino acid sequence motif at pH 7 is greater than or equal to approximately one-half of the length of the first amino acid sequence motif, wherein the first layer polypeptide is not a homopolymer. Further, a second layer comprises second layer polyelectrolyte comprising a nonprotein polyelectrolyte having a charge opposite that of the first layer polypeptide.
REFERENCES:
patent: 5138026 (1992-08-01), Miyasaka et al.
patent: 5162486 (1992-11-01), Follmann et al.
patent: 5686113 (1997-11-01), Speaker et al.
patent: 5705222 (1998-01-01), Somasundaran et al.
patent: 5747334 (1998-05-01), Kay et al.
patent: 6020175 (2000-02-01), Onda et al.
patent: 6022500 (2000-02-01), John et al.
patent: 6107084 (2000-08-01), Onda et al.
patent: 6268222 (2001-07-01), Chandler et al.
patent: 6309701 (2001-10-01), Barbera-Guillem
patent: 6316084 (2001-11-01), Claus et al.
patent: 6437095 (2002-08-01), Lilie et al.
patent: 6447887 (2002-09-01), Claus et al.
patent: 6479146 (2002-11-01), Caruso et al.
patent: 6485703 (2002-11-01), Cote et al.
patent: 6699501 (2004-03-01), Neu et al.
patent: 6743321 (2004-06-01), Guralski et al.
patent: 6743521 (2004-06-01), Hubbell et al.
patent: 6833192 (2004-12-01), Caruso et al.
patent: 6989267 (2006-01-01), Kim et al.
patent: 7045146 (2006-05-01), Caruso et al.
patent: 7056554 (2006-06-01), Voigt et al.
patent: 7101575 (2006-09-01), Donath et al.
patent: 2002/0037383 (2002-03-01), Spillman, Jr. et al.
patent: 2003/0124368 (2003-07-01), Lynn et al.
patent: 2003/0211129 (2003-11-01), Spillman, Jr. et al.
patent: 2004/0013721 (2004-01-01), Antipov et al.
patent: 2004/0013738 (2004-01-01), Voigt et al.
patent: 2005/0037050 (2005-02-01), Weber
patent: 2005/0058603 (2005-03-01), Gao et al.
patent: 2005/0069950 (2005-03-01), Haynie
patent: 2005/0129727 (2005-06-01), Weber et al.
patent: 2005/0180945 (2005-08-01), Chaikof et al.
patent: 0 667 148 (1985-08-01), None
patent: 0 415 273 (1990-08-01), None
patent: 0 433 428 (1991-08-01), None
patent: 0 472 990 (1991-08-01), None
patent: 1 116 516 (2001-07-01), None
patent: 0 823 331 (2001-11-01), None
patent: 2 135 954 (1984-09-01), None
patent: WO 99/47252 (1999-09-01), None
patent: WO 99/47253 (1999-09-01), None
patent: WO 00/03797 (2000-01-01), None
patent: WO 00/77281 (2000-12-01), None
patent: WO 02/09864 (2002-02-01), None
patent: WO 02/09865 (2002-02-01), None
patent: WO 02/017888 (2002-07-01), None
Chluba et al. “Peptide Hormone Covalently Bound to Polyelectrolytes and Embedded into Multilayer Architectures Conserving Full Biological Activity,” Biomacromolecules, 2001, 2, 800-5.
Pishko et al. “Mass Transfer in Amperometric Biosensors Based on Nanocomposite Thin Films of Redox Polymers and Oxidoreductases,” Sensors, 2002, 79-90.
Lactate oxidase [gi:849022], http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=protein&id=849022, printed Feb. 5, 2009.
Glucose oxidase [gi:110294440], http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=protein&id=110294440, printed Feb. 5, 2009.
Pyruvate oxidase [gi:1009025], http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=protein&id=1009025.
Picart et al; “Primary Cell Adhesion on RGD-Functionalized and Covalently Crosslinked Thin Polyelectrolyte Multilayer Films”; Advanced Functional Materials; 15; pp. 83-94; (2005).
Tilman M. Hackeng et al; “Protein Synthesis by Native Chemical Ligation: Expanded Scope by Using Straightforward Methodology”; Proc. Natl. Acad. Sci.; USA; 96; pp. 10068-10073; (1999).
Michael S. Wong et al; “Assembly of Nanoparticles into Hollow Spheres Using Block Copolypeptides”, Nano Letters; 2; pp. 583-587; (2002).
Glinel et al.; “Polyelectrolyte Multilayers Based on Amphiphilic Polysaccharides: Application for Entrapment and Release of Hydrophobic Molecules”; Abstracts of Papers, American Chemical Society; 230; p. 28; (2005).
Haynie, et al.; “Protein-Inspired Multilayer Nanofilms: Science, Technology and Medicine”; Nanomedicine: Nanotechnology, Biology, and Medicine; 2; pp. 150-157; (2006).
Li, et al; “Multilayer Biomimetics: Reversible Covalent Stabilization of a Nanostructured Biofilm”; Biomacromolecules; 5; pp. 1667-1670; (2004).
Zheng, et al; “Design of Peptides for Thin Films, Coatings and Microcapsules for Applications in Biotechnology”; Journal of Biomaterials Science Polymer Edition; 16; pp. 285-299; (2005).
International Search Report and Written Opinion; International Application No. PCT/US2006/041713; International Filing Date Oct. 25, 2006; Applicant's File Reference ATE-0002P2-PCT; Date of Mailing Apr. 23, 2008, 16 pages.
Chou Fasman Parameters, http://prowl.rockefeller.edu/aainfo/chou.htm; Jun. 29, 2008; 2 pages.
Pathak et al; “Structure of the B-Subunit of Translation Initiation Factor elF-2”; Cell; 54; pp. 633-639; CAS 1989: 167098; one page.
Konecki et al.; “The Primary Structure of Human Chromiogranin A and Pancreastatin”; J. Biol. Chem.; 262; pp. 17026-17030; (1987).
Arora, et al.; “Design of Artificial Transcriptional Activators with Rigid Poly-L-Proline Linkers”; J. Am. Chem. Soc.; 124; pp. 13067-13071; (2002).
Boulmedais, et al.; “Secondary Structure of Polypeptide Multilayer Films: An Example of Locally Ordered Polyelectrolyte Multilayers”; Langmuir; 18; pp. 4523-4525; (2002).
Cheng, et al.; “Ultrathin Polypeptide Multilayer Films for the Fabrication of Model Liquid/LiquidElectrochemical Interfaces”; J. Phys. Chem. B; 103; pp. 8726-8731; (1999).
Cooper, et al.; “Thermodynamic Consequences of the Removal of a Disulphide Bridge from Hen Lysozyme”; J. Mol. Bio. 225; pp. 939-943; (1991) Abstract Only.
Fermi, et al.; “The Crystal Structure of Human Deoxyhaemoglobin at 1.74 Å Resolution”; J. Mol. Biol.; 175; pp. 159-174; (1984).
Greaser; “Identification of New Repeating Motifs in Titin”; Proteins: Structure, Function, and Genetics; 43; pp. 145-149; (2001).
Hong, et al.; “The Effect of Charge Increase on the Specificity and Activity of a Short Antimicrobial Peptide”; Peptides; 22; pp. 1669-1674; (2001).
Hugli; “Human Anaphylatoxin (C3a) From the Third Component of Complement”; J. Biol. Chem.; 250; pp. 8293-8301; (1975).
Jöns, et al.; “Identification of the Binding Interface Involved in Linkage of Cytoskeletal Protein 4.1 to the Erythrocyte Anion Exchanger”; The EMBO Journal; 11; pp. 2863-2867; (1992).
Nagi; et al.; “An Inverse Correlation Between Loop Length and Stability in a Four-Helix-Bundle Protein”; Folding & Design; 2; pp. 67-75; (1997).
Ohkawa, et al.; “Biodegradation of Ornithine-Containing Polylysine Hydrogels”; Biomaterials; 19; pp. 1855-1860; (1998).
Oppenheim; et al.; “Histatins, A Novel Family of Histidine-Rich Proteins in Human Parotid Secretion”; J. Biol. Chem.; 263; pp. 7472-7477; (1988).
Qiu, et al.; “Studies on the Drug Release Properties of Polysaccharide Multilayers Encapsulated Ibuprofen Microparticles”; Langmuir; 17; pp. 5375-5380; (2001).
Rado, et al.; “Isolation of Lactoferrin cDNA From a Human Myeloid Library and Expression of mRNA During Normal and Leukemic Myelopoiesis”; Blood; 70; pp. 989-993; (1987).
Sauerbrey; The Use of Quartz Oscillators for Weighing Thin Layers and for Microweighting; Z. Physik; 155; pp. 206-222; (1959); Abstract only; 1 page.
Schierholz; et al.; “Implant infections: A Haven for Opportunistic Bacteria”; Journal of Hospital Infection; 49; pp. 87-93; (2001).
Sugimoto, et al.; “The Amino Acid Sequence of a Glutamic Acid-Rich Pro
Bradley Christina Marchetti
Cantor & Colburn LLP
Louisiana Tech University Foundation, Inc.
Tsang Cecilia
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