Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Stent structure
Patent
1988-08-09
1990-02-20
Apley, Richard J.
Prosthesis (i.e., artificial body members), parts thereof, or ai
Arterial prosthesis
Stent structure
623 66, A61F 124
Patent
active
049022890
ABSTRACT:
Process for forming a multilayer blood vessel prosthesis. Each layer is formed from bioreplaceable materials which include those produced by contacting collagen with an aminopolysaccharide and subsequently covalently crosslinking the resluting polymer, polymers of hydroxyacetic acid and the like. Cross flow filtration molding and wet extrusion molding are two processes which are particularly useful for forming the inner layer of the blood vessel prosthesis. The outer layer of the blood vessel prosthesis is preferably formed by freeze drying a dispersion of the bioreplaceable material onto the inner layer(s). The disclosed blood vessel prosthesis is a multilayer structure with each layer having a porosity and other physicochemical and mechanical characteristics selected to maximize the effectiveness of the blood vessel. The prosthesis funcitons initially as a thromboresistant conduit with mechanical properties which match those of the adjacent natural blood vessel. Eventually, the prosthesis functions as a regeneration template which is replaced by new connective tissue that forms during the healing process following attachment of the prosthesis.
REFERENCES:
patent: 4252759 (1981-02-01), Yannas et al.
patent: 4280954 (1981-07-01), Yannas et al.
patent: 4286341 (1981-09-01), Greer et al.
patent: 4522753 (1985-06-01), Yannas et al.
patent: 4539716 (1985-09-01), Bell
Apley Richard J.
Cook Paul J.
Isabella David J.
Massachusetts Institute of Technology
LandOfFree
Multilayer bioreplaceable blood vessel prosthesis does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Multilayer bioreplaceable blood vessel prosthesis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multilayer bioreplaceable blood vessel prosthesis will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1613683