Multilayer analytical element having an impermeable radiation di

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals

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422 56, 422 57, 427 2, 435 7, 435805, 436170, 436810, G01N 3352, G01N 3354

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043903436

ABSTRACT:
A multilayer analytical element for detecting a ligand in or the ligand binding capacity of a liquid sample of the type having a reagent layer incorporating reagents which are responsive to the ligand in or the ligand binding capacity of the sample to give a detectable response, a radiation diffusing and blocking layer, and a support layer, the improvement wherein the radiation diffusing and blocking layer is (a) interposed between the reagent layer and the support layer; (b) impermeable to the ligand, reagents of the reagent layer, and products of their interreaction; and (c) inert to the ligand, reagents of the reagent layer, and products of their interreaction.

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