Multilayer analytical element and method of making, using ultras

Adhesive bonding and miscellaneous chemical manufacture – Methods – Surface bonding and/or assembly therefor

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156 733, 1562728, 422 56, 435805, G01N 3122, B32B 3116, B32B 3118

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active

047769041

ABSTRACT:
A method of making a multilayer analytical test element comprises providing layers at least one of which is responsive to detect a ligand in a liquid sample, or to detect the ligand binding capacity of the sample, and at least one other layer that is fusible when subjected to sonic energy, arranging the layers one on top of the other together to form a composite blank of layers, subjecting the composite to ultrasonic or laser energy to cut the composite to the desired dimension of the test element and to simultaneously weld the layers at the edges thereof, said energy softening and fusing the fusible layer to thereby bond the layers together.

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patent: 4230757 (1980-10-01), Toner
patent: 4478661 (1984-10-01), Lewis
patent: 4543154 (1985-09-01), Reiter
patent: 4678640 (1987-07-01), Hamano et al.

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