Multifunctional recombinant phycobiliprotein-based...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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C435S069100, C435S320100, C435S252100, C435S007700, C530S350000, C536S023100, C436S501000

Reexamination Certificate

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10617208

ABSTRACT:
The invention provides multifunctional fusion constructs which are rapidly incorporated into a macromolecular structure such as a phycobilisome such that the fusion proteins are separated from one another and unable to self-associate. The invention provides methods and compositions for displaying a functional polypeptide domain on an oligomeric phycobiliprotein, including fusion proteins comprising a functional displayed domain and a functional phycobiliprotein domain incorporated in a functional oligomeric phycobiliprotein. The fusion proteins provide novel specific labeling reagents.

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patent: 98/23737 (1998-06-01), None
patent: 01/96871 (2001-12-01), None
Database CA Online!, Chemical Abstracts Service, Qin, Song et al., retrieved from STN Database Accession No. 132:19595 HCA.
Mosley, David et al., Nov. 5, 1997, Photochemistry and Photobiology 66(5):710-15.
Cherry, Richard et al., Jan. 12, 1998, Journal of Cell Biology 140(1):71-79.
Cai, Yuping et al., Mar. 15, 2001, Analytical Biochemistry 290(2):186-204.
The University of Tulsa Graduate School Dissertation by Colleen Mary Tool, Process and Structure in the Assembly of a Cyanobacterial Light-Harvesting Complex, UMI No. 9839498.
Abstract: UMIProQuest Publication No. AAT 9839498, Toole, Colleen Mary, Process and Structure in the Assembly of a Cyanobacterial Light-Harvesting Complex, Jan. 1999.

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