Multifunctional M-CSF proteins and genes encoding therefor

Details Multifunctional M-CSF proteins and genes encoding therefor Multifunctional M-CSF proteins and genes encoding therefor

1994-12-12

1996-10-22

Allen, Marianne P.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435 6951, 435 6952, 435 697, 4352523, 4353201, 536 234, 536 235, 536 2352, C12N 1500, C12N 1524, C12N 1520, C12N 1527

Patent

active

055676111

ABSTRACT:
Multifunctional proteins having M-CSF activity and at least one other bioactivity not found together in a single naturally occuring molecule are described. These multifunctional M-CSF proteins can be produced by the expression of fused genes which are also described. These multifunctional M-CSF proteins have increased therapeutic potential.

REFERENCES:
patent: 4468382 (1984-08-01), Bacha et al.
patent: 4518584 (1985-05-01), Mark et al.
patent: 4545985 (1985-10-01), Pastan et al.
patent: 4675382 (1987-06-01), Murphy
patent: 4703008 (1987-10-01), Lin
patent: 4738927 (1988-04-01), Taniguchi et al.
patent: 4752585 (1988-06-01), Koths et al.
patent: 4758428 (1988-07-01), Mark et al.
patent: 4762791 (1988-08-01), Goeddel et al.
patent: 4762914 (1988-08-01), Auron et al.
patent: 4778879 (1988-10-01), Mertelsmann et al.
patent: 4929700 (1990-05-01), Halenbeck et al.
patent: 5013653 (1991-05-01), Huston et al.
patent: 5084556 (1992-01-01), Brown
patent: 5171675 (1992-12-01), Cerretti et al.
Habermann, P., Inpadoc abstract for EPO 288809 (Nov. '88).
Habermann, P., Derwent abstract for EPO 288809 (Nov. '88).
Tonouchi et al., 1988, J. Biochem., 104:30-34.
Sideras et al., 1988, Immunological Reviews, 102:189-212.
Kaushansky et al., 1986, PNAS (USA), 83:3101-3105.
Feng, G-S. et al., 1988, Science 241:1501-1503.
Kelley, V. E. et al., 1988, Proc. Natl. Acad. Sci. USA 85:3980-3984.
Ralph, P. et al., 1986, Blood 68:633-639.
Pirker, R. et al. 1985, J. Clin. Invest. 76:1261-1267.
Veronese, F. et al., 1985, Applied Biochem. & Biotech 11:141-152.
Ralph, P. et al., in The Year in Immunology 1988, Cruse et al., eds., Basel, Karger, 1989, vol. 5, pp. 103-125.
Ralph, P. "Colony Stimulating Factors", in Human Monocytes, Asherson et al. eds., Academic Press, 1989, pp. 227-246.
Metcalf, D., 1970, J. Cell. Physiol. 76:89-100.
Das, S. K. et al., 1981, Blood 58:630-641.
Das, S. K. et al., 1982, J. Biol. Chem. 257:13679-12681.
Stanley, E. R. et al., 1977, J. Biol. Chem. 252:4305-4312.
Wong, G. G. et al., 1987, Science 235:1504-1508.
Kawasaki, E. S. et al., 1985, Science 230:291-296.
Ladner, M. B. et al., 1987, EMBO J. 6:2693-2698.
Cerretti, D. P. et al., 1988, Molecular Immunol. 25:761-770.
Takahashi, M. et al., 1988, Bioch. Biophs. Res. Comm. 152:1401-1409.
Taniguchi, T. et al., 1983, Nature 302:305-110.
Devos et al., 1983, Nucleic Acids Res. 11:4307-4323.
Ceretti et al., 1986, Proc. Natl. Acad. Sci. USA 83:3223-3227.
Chemical Abstracts, 1987, 106:(21):170236f (abstract of Japanese Patent Publication No. 61/225199).

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