Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1995-09-29
2000-07-04
Housel, James C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
536 41, 435842, 514 25, 514885, A61K 3908
Patent
active
060835125
ABSTRACT:
Novel multicomponent clostridial vaccine formulations using readily dispersible, non-depot adjuvants, such as saponin, are disclosed. The vaccines can be administered to cattle intramusculary or subcutaneously without the severe persistent local reactions, such as granulomas, abscesses, and scarring, normally seen with other multicomponent clostridial vaccines.
REFERENCES:
patent: 3883425 (1975-05-01), Dorn
patent: 4292307 (1981-09-01), Zemlyakova
patent: 4981684 (1991-01-01), MacKenzie et al.
patent: 5043158 (1991-08-01), Sleytr et al.
patent: 5084269 (1992-01-01), Kullenberg
patent: 5593697 (1997-01-01), Barr et al.
patent: 5736139 (1998-04-01), Kink et al.
Thomson et al., 1976, Develop. Biol. Standard, 32:265-269.
Reynolds et al., 1990, Veterinary Immunology and Immunopathology, 25:167-175.
The Merck Veterinary Manual, 5th ed., 1979, pp. 396-409, Merck & Co., Rahway, NJ.
Thomson et al., 1969, "Immunogenicity of a multicomponent clostridial oil emulsion vaccine in sheep", Vet. Rec., 85:81-85 (1969).
Thomson et al., 1953, Vet. Rec., 65:(42):659-663.
Sterne et al., 1962, "Immunisation of sheep with multi-component clostridial vaccines", Vet. Rec., 74(34):909-913.
Kerry et al., 1979, Vet. Rec., 105:551-554.
Lozano, E. A., 1981, Am. J. Vet. Res., 42(9):1641-1644.
Webster et al., 1985, Australian Vet. J., 62(4):112-114.
Farrag et al., 1987, Assiut Vet. Med. J., 18(36):73-83.
Awad et al., 1986, Assiut Vet. Med. J., 17(34):202-214.
Dalsgaard, K., 1974, "Saponin adjuvants", Archiv. gesamte virusforschung 44:243-254.
Baharsefat et al (1976), Arch. Inst. Razis vol. 28, pp. 51-56.
Seifert et al, Deutsche Tierarztliche Wochenschrift, vol. 90, (7), pp. 274-279, 1983.
Alpha-7 product insert, Anchor.TM., Boehringer Ingelheim Animal Health Inc., 1992.
Green et al., The Veterinary Record, May 2, 1987 pp. 435-439.
Haas, H F, Develop. Biol. Standard., vol. 32, pp. 167-172, 1976.
Marciani et al Vaccine 9:89-96, 1991.
Kensil et al J. Immunol 146(2):431-437, 1991.
Ginsburg Paul G.
Housel James C.
Koller Alan L.
Portner Ginny Allen
Richardson Peter C.
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