Liquid purification or separation – Casing divided by membrane into sections having inlet – Dialyzer with dialysate proportioning means
Reexamination Certificate
2007-01-02
2007-01-02
Menon, Krishnan S. (Department: 1723)
Liquid purification or separation
Casing divided by membrane into sections having inlet
Dialyzer with dialysate proportioning means
C210S321750, C210S321720, C422S105000, C422S105000, C435S297100, C435S297200, C435S297500
Reexamination Certificate
active
10652938
ABSTRACT:
The invention is a multichamber microdialysis device with a multitude of sample chambers in close side by side arrangement (similar to a microtiter plate) for receiving liquid samples, and at least one dialysate chamber for receiving a dialysate liquid. The sample chambers are surrounded by circumferential sidewalls and are in liquid exchange contact to a neighboring dialysis chamber via an exchange opening covered by a semipermeable membrane. The semipermeable membrane is fixed liquid-tight to the walls of the sample chamber, so that a diffusion exchange between the sample chamber and the correspondingly neighboring dialysate chamber is only possible via the membrane. Consequently, only molecules with a molecular weight below the molecular cut-off of the semipermeable membrane can diffuse from the sample chamber to the dialysate chamber or from the dialysate chamber to the sample chamber.
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Buchberger Bernd
Fischer Ulrike
Menzler Horst
Schels Hans
Watzele Manfred
Amick Marilyn L.
Menon Krishnan S.
Roche Diagnostics Operations Inc.
Roche Diagnostics Operations Inc.
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