Multiblock biodegradable hydrogels for drug delivery and...

Details Multiblock biodegradable hydrogels for drug delivery and... Multiblock biodegradable hydrogels for drug delivery and...

2007-07-31

2007-07-31

Yoon, Tae H (Department: 1714)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

C524S504000, C524S505000

Reexamination Certificate

active

11158565

ABSTRACT:
Gel-forming macromers including at least four polymeric blocks, at least two of which are hydrophobic and at least one of which is hydrophilic, and including a crosslinkable group are provided. The macromers can be covalently crosslinked to form a gel on a tissue surface in vivo. The gels formed from the macromers have a combination of properties including thermosensitivity and lipophilicity, and are useful in a variety of medical applications including drug delivery and tissue coating.

REFERENCES:
patent: 5429826 (1995-07-01), Nair et al.
patent: 5573934 (1996-11-01), Hubbell et al.
patent: 6201065 (2001-03-01), Pathak et al.

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