Multiblock biodegradable hydrogels for drug delivery and...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices

Reexamination Certificate

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C424S487000, C424S078060, C424SDIG001, C524S504000, C524S505000, C524S916000, C525S079000, C525S090000, C525S093000, C525S383000, C525S941000

Reexamination Certificate

active

06923986

ABSTRACT:
Gel-forming macromers including at least four polymeric blocks, at least two of which are hydrophobic and at least one of which is hydrophilic, and including a crosslinkable group are provided. The macromers can be covalently crosslinked to form a gel on a tissue surface in vivo. The gels formed from the macromers have a combination of properties including thermosensitivity and lipophilicity, and are useful in a variety of medical applications including drug delivery and tissue coating.

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