Multiaxis focusing mechanism for microarray analysis

Details Multiaxis focusing mechanism for microarray analysis Multiaxis focusing mechanism for microarray analysis

2011-01-18

2011-01-18

Forman, B J (Department: 1634)

Chemistry: molecular biology and microbiology

Apparatus

C435S286200, C435S287200, C435S288700, C422S068100, C422S082050, C422S082080

Reexamination Certificate

active

07871810

ABSTRACT:
Systems and methods for positioning a multi-featured biological array relative to a signal acquisition device. Detection of the array's positional deviation may be achieved by a calibration beam reflected from the array surface and detected by a position sensitive detector (PSD). The PSD-measured positional deviation can be transformed and used in a control loop to correct for positional variations of the array. The calibration beam and PSD may also be used to detect the array or feature boundaries, thereby allowing lateral centering or positioning of the array relative to the signal acquisition device.

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