Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Patent
1999-03-03
2000-08-01
Redding, David A.
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
4352877, 4352879, 435805, C12M 134
Patent
active
060965339
ABSTRACT:
The present specification describes a sterility indicator device which comprises a container means and a cover means. The container means comprises a plurality of discrete zones, wherein each zone contains biologically active substrate useful in determining the effectiveness of a sterilization process. Each zone is in effect an individual sterility indicator. The device results in increased reliability and accuracy due to the increased number of discrete zones. The number of discrete zones may be of sufficient size so as to provide statistically significant predictive values at the ninety-five percent or better confidence interval for lower numbers of surviving spores.
REFERENCES:
patent: 2998306 (1961-08-01), Huyck et al.
patent: 3585112 (1971-06-01), Ernst
patent: 3661717 (1972-05-01), Nelson
patent: 3752743 (1973-08-01), Henshilwood
patent: 4087326 (1978-05-01), Kereluk
patent: 4245043 (1981-01-01), Lund
patent: 4252904 (1981-02-01), Nelson et al.
patent: 4345028 (1982-08-01), Nelson et al.
patent: 4839291 (1989-06-01), Welsh et al.
patent: 5073488 (1991-12-01), Matner et al.
patent: 5252484 (1993-10-01), Matner et al.
patent: 5366872 (1994-11-01), Hird et al.
patent: 5536662 (1996-07-01), Humphries et al.
patent: 5922592 (1999-07-01), Tautvydas
Article: Hanlon et al., "Quantitative Assessment of Sterilization Efficiency Using Lyophilized Calcium Alginate Biological Indicators," Letters in Applied Microbiology, 17, 1993, pp. 171-173.
Article: Dadd et al., "Germination of Spores of Bacillus subtilis var. niger Following Exposure to Gaseous Ethylene Oxide," Journal of Applied Bacteriology, 60, 1986, pp. 425-433.
Article: Foster et al., "Pulling the Trigger: The Mechanism of Bacterial Spore Germination," Molecular Microbiology, 4(1), 1990, pp. 137-141.
Article: Umeda et al., "Spore Outgrowth and the Development of Flagella in Bacillus subtilis, " Journal of General Microbiology, 118, 1980, pp. 215-221.
Chapter: Pflug et al., "Principles of the Thermal Destruction of Microorganisms," Disinfection, Sterilization, and Preservation, Fourth Edition, Chapter 6, 1991, pp. 85-128.
Chapter: Parisi et al.; "Sterilization with Ethylene Oxide and Other Gases," Disinfection, Sterilization, and Preservation, Fourth Edition, Chapter 33, 1991, pp. 580-595.
Article: Fred et al., "The Reduction of 2,3,5-Triphenyltetrazolium Chloride by Pencillium chrysogenum.sup.1," Science, vol. 109, Feb. 18, 1949, pp. 169-170.
Article: Urban et al., "Nitroblue Tetrazolium (NBT) Reduction by Bacteria," Acta Path. Microbiol Scand., Sect B., 87, 1979, pp. 227-233.
Article: Trevors, "Electron Transport System Activity in Soil, Sediment, and Pure Cultures," CRC Critical Reviews in Microbiology, vol. 11, Issue 2, 1984, pp. 83-101.
Article: Stellmach et al., "A Fluorescent Redox Dye. Influence of Several Substrates and Electron Carriers on the Tetrazolium Salt-Formazan Reaction of Ehrlich Ascites Tumour Cells," Histochemical Journal, 19, 1987, pp. 21-26.
Article: Rodriguez et al., "Use of a Fluorescent Redox Probe for Direct Visualization of Actively Respiring Bacteria," Applied and Environmental Microbiology, vol. 58, No. 6, Jun. 1992, pp. 1801-1808.
Article: Spicher, "Sterilization--The Microbiology Between Claim and Reality," Zbl. Hyg., 194, 1993, pp. 223-225.
Article: Spicher et al., "How Many Biological Indicators Have to be Tested to Make a Reliable Statement as to their Resistance?," Zbl. Bakt. Hyg., I. Abt. Orig. B 179, 1984, pp. 365-380.
Article: LePecq et al., "A Fluorescent Complex Between Ethidium Bromide and Nucleic Acids," J. Mol. Biol., 27, 1967, pp. 87-106.
Article: Prasad et al., "A Simple Fluorometric Method for the Determination of RNA and DNA in Tissues," The Journal of Laboratory and Clinical Medicine, vol. 80, Jul.-Dec., 1972, pp. 598-601.
Article: Tautvydas, "Evidence for Chromosome Endoreduplication in Eudorina californica, a Colonial Alga," Differentiation 5, 1976, pp. 35-42.
Standard: "American National Standard for Biological Indicators for Ethylene Oxide Sterilization Processes in Health Care Facilities," Association for the Advancement of Medical Instrumentation, 1986.
Chapter: Pflug, "Description, Establishment, and Statistical Characteristics of the Endpoint of a Microbial Preservation Process," Chapter 4, pp. 4.1-4.20.
Article: Reich, "Effect of Sublethal Ethylene Oxide Exposure on Bacillus subtilis Spores and Biological Indicator Performance," Journal of the Parenteral Drug Association, vol. 34, No. 3, May-Jun. 1980, pp. 200-211.
3M Innovative Properties Company
Redding David A.
Rogers James A.
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