Chemical apparatus and process disinfecting – deodorizing – preser – Control element responsive to a sensed operating condition
Patent
1998-01-30
2000-11-07
Beisner, William H.
Chemical apparatus and process disinfecting, deodorizing, preser
Control element responsive to a sensed operating condition
4352884, 4353053, 356246, 250328, 220 232, 220 234, B01L 300
Patent
active
061432504
DESCRIPTION:
BRIEF SUMMARY
TITLE OF THE INVENTION
1. Field of the Invention
The present invention relates to a container which is suitable for an analysis inspection which requires a high quantitative accuracy. More particularly the present invention relates to the container by which all of the quantity of a specimen in the container can be substantially completely aspirated with being disposed a front end portion of a pipette tip in contact with a surface of the inside bottom of the container. Moreover, the present invention relates to the container which can largely enhance an efficiency of agitating by uniforming a diffusion of the specimen on the occasion of discharging it.
2. Background of the Invention
In order to maintain a precision of an analysis in a high level, as is well-known, a quantitative precision by a pipette device must be exactly maintained. In case of a conventional container, an inside bottom part of the container is formed so as to have a plane surface or a vertical sectional shape being semicircle or substantially U-like. Therefore, aspirating or discharging a sample and/or a reagent can not be executed in a state that a front end part of a pipette tip remains to be disposed in contact with the inside bottom part of the container. As a result, aspirating or discharging a sample and a reagent can be executed in a situation that the front end part of the pipette tip is kept to be lifted from the inside bottom part of the container slightly. Consequently, a small amount of samples and reagents always remains behind the container. In order to compensate this remaining amount, more amount than the actually necessary amount of aspirating needs be aspirated and/or discharged by the pipette tip. Thus, it is inevitable that samples or reagents being not aspirated remain behind the container. As a result, it has a problem that a high quantitative analysis can not be executed.
A conventional means to solve such a problem is shown in FIG. 16 for example. A front end part 2 of a pipette tip 1 is cut diagonally in order to be able to aspirate and discharge a sample S in a state that the front end part 2 of the pipette tip 1 is disposed in contact with an inside bottom part 4 of a container 3. Also, as shown in FIG. 18, another conventional means in which has one or more caves 5 are mounted in the front end part of the pipette tip 1, is proposed. It is designed so that an opening of the pipette tip 1 can not be blockaded by the contact with the inside bottom part 4 of the container 3.
But, even if the front end part 2 of the pipette tip 1 is cut diagonally, the liquid below a level W in FIG. 16 slightly lower than an upper rim of the opening of the front end part which is cut diagonally, can not be completely aspirated. As shown in FIG. 17, when the aspirated samples and/or reagents are discharged in the container 3, those in the one side of the container 3 are agitated by the pressure of discharging. But, the other side of container 3 which does not face the above-mentioned opening cut diagonally, is not directly affected by the pressure of discharging. Therefore, the conventional means has a problem that the agitating efficiency on the opposite side of the opening is low and it is difficult to get a uniform agitating effect, i.e. a uniform state of reaction. Also, it has a problem that manufacture of the pipette tip is not easier and a cost of manufacture increases.
In the same way, the conventional means which is bored by caves 5 in the front end part of the pipette tip 1, cannot aspirate a liquid S below the position where the caves 5 are bored, too. Also, when the aspirated liquid is discharged, the liquid is discharged only in the direction of the opening of the caves 5. Therefore, the conventional means has the problem that it is difficult to get a uniform agitating effect. Moreover, as the manufacturing step to bore one or more caves 5 is necessary, the conventional means has a problem that the manufacture of pipette tip 1 is complicated and a manufacture cost increases.
When liquid is aspirated and discharged in a
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Beisner William H.
Precision System Science Co., Ltd.
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