Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1994-05-31
1995-02-07
Kishore, G. S.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424453, 424464, 424466, 424468, 424470, A61K 922
Patent
active
053874218
ABSTRACT:
A drug delivery system includes a first capsule half having an inner chamber for containing a drug therein. A plug is disposed in a passageway of the capsule half for plugging the opening thereof. The plug is releasable from the passageway opening upon the application of pressure from within the inner chamber. A pump mechanism causes an increase in pressure within the inner chamber and forces the plug out of the passageway to release the drug from the inner chamber and out of the passageway thereby providing a second pulse of drug release at a predetermined time after initial ingestion of the capsule. The invention further provides a method of manufacturing the drug delivery system and method by which the drug delivery system provides the drug to the body.
REFERENCES:
patent: 4865849 (1989-09-01), Conte
Amidon Gordon L.
Leesman Glen D.
Sherman Lizbeth B.
Bawa Raj
Kishore G. S.
TSRL, Inc.
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