Multi-stage cascade boosting vaccine

Details Multi-stage cascade boosting vaccine Multi-stage cascade boosting vaccine

2005-08-09

2005-08-09

Huff, Sheela J. (Department: 1642)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Animal or plant cell

C424S093200, C424S093710, C424S130100, C424S131100, C536S023400

Reexamination Certificate

active

06926893

ABSTRACT:
Humoral and cellular immune responses against tumor cells and infectious agents are induced in a mammal using a vaccine comprising antibodies and anti-idiotype antibodies that mimic an epitope of antigen that is associated with a tumor or infectious agent. Antibodies and cytokines also may be used to amplify the immune cascade. Moreover, antibodies and anti-idiotype antibodies can be used to produce T cells that are not MHC-restricted and that are targeted to tumor cells and infectious agents.

REFERENCES:
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patent: 6132718 (2000-10-01), Hansen
patent: 15322 (1992-09-01), None
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Losman et al. Int. J. Cancer vol. 56 p. 580 (1994).
Riott et al Immunology, 3rd Edition, pp. 7.8-7.14 (Mosby, 1993).

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