Multi-stage cascade boosting vaccine

Details Multi-stage cascade boosting vaccine Multi-stage cascade boosting vaccine

1994-07-06

1998-08-25

Loring, Susan A.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

4241311, 4241331, 4241361, 4241501, 4241511, 4241551, 4241561, 4241591, 5303871, 5303872, 5303873, 5303882, 5303883, 5303884, 5303885, 5303886, 5303888, 53038885, A61K 39395, A61K 3940, C07K 1600

Patent

active

057981000

ABSTRACT:
Humoral and cellular immune responses against tumor cells and infectious agents are induced in a mammal using a vaccine comprising antibodies and anti-idiotype antibodies that mimic an epitope of antigen that is associated with a tumor or infectious agent. Antibodies and cytokines also may be used to amplify the immune cascade. Moreover, antibodies and anti-idiotype antibodies can be used to produce T cells that are not MHC-restricted and that are targeted to tumor cells and infectious agents.

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