Chemistry: analytical and immunological testing – Optical result – With reagent in absorbent or bibulous substrate
Patent
1988-07-07
1991-03-26
Arnold, Bruce Y.
Chemistry: analytical and immunological testing
Optical result
With reagent in absorbent or bibulous substrate
350534, 350536, 436174, G01N 2101, G01N 100, G02B 2134
Patent
active
050023772
ABSTRACT:
A process for producing a slide bearing a spaced array of specimen fragments which comprises (i) cutting at least one specimen into a plurality of narrow strips; (ii) separating the plurality into groups of specimen strips; (iii) separately positioning strips from the groups in parallel grooves in a mold; (iv) embedding the strips in the mold in a first embedding medium to provide a structure comprising a base member having opposed first and second surfaces, the first surface being substantially planar; the second surface having ridges containing a specimen strip extending therefrom; (v) forming a stack of elements, each element corresponding to the structure, with the terminal surface of the ridges of an upper structure abutting the substantially planar first surface of the next lower structure; the spaces between the ridges defining channels for receipt of a fluid; (vi) embedding the stack in a second embedding medium to form a block having a spaced array of parallel specimen strips embedded therein; the strips being so arranged that a section of the block includes a spaced array of cross-sections of each of the embedded specimen strips; (vii) dividing the block into sections each containing a spaced array of cross-sections of each of the embedded specimen strips; (viii) mounting at least one of such block sections on a slide.
REFERENCES:
patent: 3736042 (1973-05-01), Markovits et al.
patent: 3832135 (1974-08-01), Drozdowski et al.
patent: 4647543 (1987-03-01), Stocker
patent: 4856073 (1989-08-01), Farber et al.
Battifora Hector A.
Mehta Parula
Arnold Bruce Y.
City of Hope
Irons Edward S.
Phan James
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