Plastic and nonmetallic article shaping or treating: processes – Pore forming in situ
Reexamination Certificate
2007-12-18
2007-12-18
Warden, Jill (Department: 1743)
Plastic and nonmetallic article shaping or treating: processes
Pore forming in situ
C422S105000, C422S105000, C210S321600, C210S500220, C210S500270
Reexamination Certificate
active
10689121
ABSTRACT:
Sample preparation device and method for desalting and concentrating samples prior to further analysis such as by MALDI TOF and/or electro-spray ionization (ESI) mass spectrometry. The device in accordance with an embodiment of the present invention contains a three dimensional structure preferably comprising a plurality of sorptive particles entrapped in a porous polymer matrix so as to form a device capable of carrying out solid phase extraction. The device is manufactured by introducing casting solution containing polymer and optionally particles into a housing, and subsequently exposing the device to a quench bath for a time sufficient to allow for solvent exchange and precipitation to form the composite structure in the housing. The present invention is also directed towards a method of sample preparation using the device of the present invention.
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Brewster David
Clark Phillip
Kopaciewicz William
Handy Dwayne K
Millipore Corporation
Nields & Lemack
Warden Jill
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