Chemistry: analytical and immunological testing – Composition for standardization – calibration – simulation,... – Particle count or volume standard or control
Patent
1982-07-06
1985-06-04
Gron, Teddy S.
Chemistry: analytical and immunological testing
Composition for standardization, calibration, simulation,...
Particle count or volume standard or control
435 2, 435188, 424101, 436 15, 436 16, 436 17, 436 18, 436 63, G01N 3348, C09K 300
Patent
active
045215189
ABSTRACT:
An isotonic multipurpose blood diluent, and a method for use of this diluent with a weak lysing reagent system which is especially suitable for routine enumeration of traditional hemogram values, and also the determination of lymphoid-myeloid populations of leukocytes, particularly in automatic particle counting systems.
This blood diluent is capable of affording accurate, reproducible test results. It is an osmotically balanced aqueous solution of preselected pH containing Procaine hydrochloride for maintaining erythrocyte morphology during operation, N-(2-acetamido)iminodiacetic acid (ADA) as a blood cell stabilizing agent, and bacteriostatic agents including sodium 1-hydroxypyridine-2-thione, and dimethylolurea which, together with the ADA, allow preferential determination of myeloid-lymphoid leukocytes, and other hematological values.
The lysing agent is a mixture of an aqueous solution of at least one quaternary ammonium salt having surface active properties, and an alkali metal cyanide.
REFERENCES:
patent: 2745825 (1956-05-01), Semenoff
patent: 3281366 (1976-10-01), Judge et al.
patent: 3874852 (1975-04-01), Hamill
patent: 3962125 (1976-06-01), Armstrong
patent: 4102810 (1978-07-01), Armstrong
patent: 4116635 (1978-09-01), Jaeger
patent: 4185964 (1980-01-01), Lancaster
patent: 4213876 (1980-07-01), Crews et al.
patent: 4219440 (1980-08-01), Runck et al.
patent: 4248634 (1981-02-01), Forester
patent: 4286963 (1981-09-01), Ledis et al.
patent: 4346018 (1982-08-01), Carter et al.
Love, W. J., Cellular Comp. Physiol., vol. 44, pp. 291-313, (1954).
Carter James H.
Crews Harold R.
Ledis Stephen L.
Coulter Electronics Inc.
Gron Teddy S.
Hibnick Gerald R.
Simonton Pamela A.
Sparks Meredith P.
LandOfFree
Multi-purpose blood diluent and lysing agent for differential de does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Multi-purpose blood diluent and lysing agent for differential de, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multi-purpose blood diluent and lysing agent for differential de will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-829211