Multi-optical detection system

Details Multi-optical detection system Multi-optical detection system

1990-12-13

1993-12-07

Housel, James C.

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

436164, 436172, 436527, 436528, 436531, 436805, 422681, 422 8205, 422 8208, 422 8209, 435291, G01N 3353, G01N 2101

Patent

active

052683052

ABSTRACT:
Apparatus and methods are provided for the detection of analytes. A polyunsaturated polymerized lipid layer is employed, which is anisotropic, has a member of a specific binding pair bound to an end of the lipids, and whose optical characteristics are modified upon complex formation between the specific binding pair member and its complementary member. By providing for polarized light, linear and/or circular, one can detect the presence of complex formation by the change in the optical characteristics of the film. Polarizers, analyzers, and wave plates are employed for providing for a light signal which can be analyzed and related to the presence of an analyte in a sample.

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