Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1993-08-09
1995-06-27
Spiegel, Carol A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
422 8205, 422 8209, 422 8211, 435 793, 435 794, 435 795, 435970, 436527, 436528, 436532, G01N 3353
Patent
active
054279151
ABSTRACT:
Apparatus and methods are provided for the detection of analytes. A polyunsaturated polymerized lipid layer is employed, which is anisotropic, has a member of a specific binding pair bound to an end of the lipids, and whose optical characteristics are modified upon complex formation between the specific binding pair member and its complementary member. By providing for polarized light, linear and/or circular, one can detect the presence of complex formation by the change in the optical characteristics of the film. Polarizers, analyzers, and wave plates are employed for providing for a light signal which can be analyzed and related to the presence of an analyte in a sample.
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Choate Glenda L.
Guion Todd A.
Murdoch Joseph R.
Pan Victor
Ribi Hans O.
Biocircuits Corporation
Field Bret E.
Rowland Bertram I.
Spiegel Carol A.
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