Chemistry: electrical and wave energy – Apparatus – Coating – forming or etching by sputtering
Patent
1990-09-11
1992-12-22
Niebling, John
Chemistry: electrical and wave energy
Apparatus
Coating, forming or etching by sputtering
204299R, 2041801, G01N 2726, B01D 5702
Patent
active
051731649
ABSTRACT:
A preparative scale multi-mode electrical separator, which is matrix-free and may be operated in both a batch mode and a continuous, flow-through mode is provided. It may be scaled according to the solution quantities which are to be processed. An internal cooling system whereby the process fluid is always in close proximity to a chilled surface assures an efficient heat dissipation during the separation and concentration processes and also allows the use of higher voltage gradients and shorter separation times than prior designs of electrophoretic separators. Electroosmotic mixing is reduced by providing internal, compartmentation of sample fractions, focusing is improved and focusing times are decreased. Different electrophoretic methods, including zone electrophoresis, isoelectric focusing, counterflow gradient focusing or electrodialysis, may be used with the separator. It may be applied to the purification of proteins, ions, and microorganisms, and for water purification.
REFERENCES:
patent: 3989613 (1976-11-01), Grizner
patent: 4204929 (1980-05-01), Bier
patent: 4673483 (1987-06-01), Mandle
Egen Ned B.
Sammons David W.
Sharnez Rizwan
Twitty Garland E.
BioSeparations, Inc.
Niebling John
Starsiak Jr. John S.
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